Results 21 to 30 of about 383,013 (128)

Dipeptidyl Peptidase-4 Inhibitor Sitagliptin Phosphate Accelerates Cellular Cholesterol Efflux in THP-1 Cells

open access: yes, 2023
Cholesterol efflux is a major atheroprotective function of high-density lipoproteins (HDLs) which removes cholesterol from the foam cells of lipid-rich plaques in Type 2 diabetes.
Tomohiro Komatsu   +7 more
core   +1 more source

High Cell Density Cultivation Combined with high Specific Enzyme Activity: Cultivation Protocol for the Production of an Amine Transaminase from Bacillus megaterium in E. coli

open access: yesChemBioChem, Volume 25, Issue 9, May 2, 2024.
A fed‐batch protocol is established for the production of an amine transaminase of Bacillus megaterium. Hereby, the main goal is to reach high cell densities accompanied by high titers of active enzyme. Feed rate, inducer concentration, and post‐induction temperature were key parameters of the investigation. Abstract High cell density cultivation is an
Berit Rothkranz   +6 more
wiley   +1 more source

Formulation, Development and Characterization of Transdermal Patches of Sitagliptin Phosphate [PDF]

open access: yes, 2019
Sitagliptin is a dipeptidyl peptidase 4-(DPP-4) inhibitor with glucose controlling capabilities that was effectively used for treating diabetes in the past. However, the oral administration of this drug caused such severe side effects that it was removed
Shukla, Kavita Varma   +2 more
core   +1 more source

Effect of sitagliptin phosphate on cell adhesion.

open access: yes, 2015
Comparison of the adhesion on plastic plates uncoated or coated with ECM proteins (laminin, fibronectin, type I collagen and type IV collagen), of cervical cancer cells SiHa (a) and HeLa (b) 2 h after plating in the absence (control) and presence of 0.2 ...
Alessandra Nejar Bruno (776660)   +9 more
core   +1 more source

Natursown: the finely ground high-grade phosphate for heavy crops and permanent soil fertility. [PDF]

open access: yes, 1916
Commercial booklet promoting the use of natural phosphate in agriculture.https://stars.library.ucf.edu/floridaheritage/1053/thumbnail ...
Lakeland Phosphate Company,
core  

FORMULATION AND EVALUATION OF SITAGLIPTIN PHOSPHATE LOADED ORAL POLYMERIC FLOATING MICROBEADS

open access: yes, 2021
The objective of present investigation is to prepare and optimize an oral floating alginate gel beads of Sitagliptin phosphate using sodium alginate and oils as a dispersed phase to generate a uniform emulsion to create multiple tiny chambers in the ...
Bhavana Singh and Saranjit Singha*
core   +1 more source

Introducing the crystalline phase of dicalcium phosphate monohydrate [PDF]

open access: yes, 2020
Calcium orthophosphates (CaPs) are important in geology, biomineralization, animal metabolism and biomedicine, and constitute a structurally and chemically diverse class of minerals.
T. Willhammar (23523403)   +5 more
core   +2 more sources

Sitagliptin and other ‘gliptins’ - why prescribe them? [PDF]

open access: yes, 2016
Introduction\ud \ud In 2008, the Federal Drug Administration (FDA) required all new glucose-lowering therapies to show cardiovascular safety, and this applies to the dipeptidyl peptidase (DPP)-4 inhibitors (‘gliptins’).
Dimmitt, Simon B., Doggrell, Sheila
core   +1 more source

Formulations and Evaluation of Sitagliptin Phosphate Loaded Transdermal Microspheres Gel [PDF]

open access: yes, 2018
In this present study was to formulate and evaluate sustained release microsphere gel loaded sitagliptin phosphate in order to maintain a sustained drug concentration in serum for longer period of time, which may result in enhanced absorption and thereby
Vignesh, R
core  

Formulation Design, Development and Invitro Evaluation of Fast Dissolving Tablets of Sitagliptin by Direct Compression Method [PDF]

open access: yes, 2019
The Fast Dissolving Tablets of Sitagliptin were developed successfully by direct compression method. 8 formulations were prepared with different ratios of superdisintegrants.
Neelamegarajan, R
core  

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