Results 41 to 50 of about 283,041 (288)

Bayesian modeling of recombination events in bacterial populations [PDF]

, 2008
Background: We consider the discovery of recombinant segments jointly with their origins within multilocus DNA sequences from bacteria representing heterogeneous populations of fairly closely related species.
Marttinen, P., Hanage William P, Mahenthiralingam Eshwar, Adam Baldwin, Jukka Corander, Marttinen Pekka, Hanage, William P., Pekka Marttinen, Hanage, W. P., Marttinen, Pekka, Dowson, Christopher G., Baldwin, A., Baldwin Adam, Dowson, C., Chris Dowson, Corander, J., Baldwin, Adam, Dowson Chris, William P Hanage, Eshwar Mahenthiralingam, Corander Jukka, Mahenthiralingam, Eshwar   +21 more
core   +1 more source

Characterization of the integration and modular excision of the integrative conjugative element PAISt in Streptomyces turgidiscabies Car8. [PDF]

PLoS ONE, 2014
PAISt is a large genomic island located in the chromosome of the plant pathogen Streptomyces turgidiscabies Car8. The island carries clustered virulence genes, transfers to other Streptomyces species, and integrates by site-specific recombination at the ...
Jose C Huguet-Tapia, Dawn R D Bignell, Rosemary Loria   +2 more
doaj   +1 more source

Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors [PDF]

, 2004
BACKGROUND: Inactivating genes in vivo is an important technique for establishing their function in the adult nervous system. Unfortunately, conventional knockout mice may suffer from several limitations including embryonic or perinatal lethality and the
Hermens, Wim T J M C, Lieberman, A., Eggers, R., Verhaagen, J., Sablitzky, Fred, Chakravarthy, Sridhara, Zhang, Jing Ying, Zhang, J.Y., Hermens, Wim TJMC, Zhang, Jing, Verhaagen, J, Ahmed, Bushra, Anderson, P.N., Eggers, R, Eggers, Ruben, Levelt, Christiaan, Chakravarthy, S, Levelt, C., Ahmed, BY, Verhaagen, Joost, Lieberman, A.R., Hermens, WTJMC, Lieberman, AR, Niclou, Simone P, Anderson, Patrick N., Ahmed, Bushra Y, Hermens, W.T., Niclou, SP, Anderson, PN, NICLOU, Simone P., Lieberman, A R, Zhang, JY, Anderson, Patrick N, Sablitzky, F., Levelt, C, Sablitzky, F, Niclou, S.P., Lieberman, A Robert, Chakravarthy, S., Ahmed, B.Y.   +39 more
core   +1 more source

Structure and mechanism in site-specific recombination

Current Opinion in Structural Biology, 1999
Three-dimensional structural information on the integrase family of site-specific recombinases has only recently become available, with the crystal structures of catalytic domains, full-length proteins and protein-DNA complexes of this family reported over the past two years.
D N, Gopaul, G D, Duyne
openaire   +2 more sources

Control of phage Bxb1 excision by a novel recombination directionality factor. [PDF]

PLoS Biology, 2006
Mycobacteriophage Bxb1 integrates its DNA at the attB site of the Mycobacterium smegmatis genome using the viral attP site and a phage-encoded integrase generating the recombinant junctions attL and attR.
Pallavi Ghosh, Laura R Wasil, Graham F Hatfull   +2 more
doaj   +1 more source

Efficient gene targeting and foreign DNA removal by homologous recombination in the picoeukaryote Ostreococcus [PDF]

, 2014
With fewer than 8000 genes and a minimalist cellular organization, the green picoalga Ostreococcus tauri is one of the simplest photosynthetic eukaryotes. Ostreococcus tauri contains many plant-specific genes but exhibits a very low gene redundancy.
Bouget, Francois-Yves, Verge, Valerie, Carré, Isabelle A., Schatt, Philippe, Botebol, Hugo, Blain, Stephane, Lozano, Jean-Claude, Lesuisse, Emmanuel, Carré, Isabelle A   +8 more
core   +1 more source

In vivo site-specific recombination using the β-rec/six system

BioTechniques, 2008
The prokaryotic β serine recombinase (β-rec) catalyzes site-specific recombination between two directly oriented six sites (93 bp) in mammalian cells, both in episomal and in chromosomally integrated substrates.
Pilar Servert, Vicente Díaz, Daniel Lucas, Teresa de la Cueva, Maria C. Rodriguez, Javier García-Castro, Juan C. Alonso, Carlos Martínez-A, Manuel A. González, Antonio Bernad   +9 more
doaj   +1 more source

Control of Directionality in Lambda Site Specific Recombination [PDF]

Science, 1985
The simple relation between the substrates and products of site-specific recombination raises questions about the control of directionality often observed in this class of DNA transactions. For bacteriophage lambda, viral integration and excision proceed by discrete pathways, and DNA substrates with the intrinsic property of recombining in
W, Bushman, J F, Thompson, L, Vargas, A, Landy   +3 more
openaire   +2 more sources

Recombination and its impact on the genome of the haplodiploid parasitoid wasp Nasonia

, 2013
Homologous meiotic recombination occurs in most sexually reproducing organisms, yet its evolutionary advantages are elusive. Previous research explored recombination in the honeybee, a eusocial hymenopteran with an exceptionally high genome-wide ...
Gadau, Juergen, Gibson, Joshua D., Pannebakker, Bart A., Werren, John H., Koevoets, Tosca, Judson, Andrea K., van de Zande, Louis, Rosenberg, Michael S., Desjardins, Christopher A., Niehuis, Oliver, Kennedy, Kathleen, Duggan, David, Beukeboom, Leo W., Shuker, David Michael   +13 more
core   +1 more source

Positive-negative-selection-mediated gene targeting in rice

Frontiers in Plant Science, 2015
Gene targeting (GT) refers to the designed modification of genomic sequence(s) through homologous recombination (HR). GT is a powerful tool both for the study of gene function and for molecular breeding.
Zenpei eShimatani, Ayako eNishizawa- Yokoi, Masaki eEndo, Seiichi eToki, Rie eTerada   +4 more
doaj   +1 more source