Analysis of xer Site-Specific Recombination In Vivo [PDF]
, 1992 The xer site-specific recombination system is employed in two related biological processes. The first of these roles is in resolving multimers of high copy number, randomly partitioned plasmids in order to ensure their heritable stability.
McCulloch, Richard
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Temporally-controlled site-specific recombination in zebrafish. [PDF]
PLoS ONE, 2009 Conventional use of the site-specific recombinase Cre is a powerful technology in mouse, but almost absent in other vertebrate model organisms. In zebrafish, Cre-mediated recombination efficiency was previously very low.
Stefan Hans +4 more
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A simplified mathematical model of directional DNA site-specific recombination by serine integrases [PDF]
Journal of the Royal Society Interface, 2017 Alexandra Pokhilko +2 more
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Recombination: Pieces of the site-specific recombination puzzle [PDF]
Current Biology, 1995 Understanding how nucleoprotein complexes interact with specific DNA sequences has come closer with structural and mechanistic studies of the interaction between the recombination enzyme resolvase and DNA.
Oram, M., Szczelkun, M.D., Halford, S.E.
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Predicting algorithm of attC site based on combination optimization strategy
Connection Science, 2022 Site-specific recombination systems are widely used as bioengineering tools. However, the traditional site-specific recombination system requires a consensus sequence for the specific site.
Zhendong Liu +9 more
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FLP recombinase-mediated site-specific recombination in silkworm, Bombyx mori. [PDF]
PLoS ONE, 2012 A comprehensive understanding of gene function and the production of site-specific genetically modified mutants are two major goals of genetic engineering in the post-genomic era.
Ding-Pei Long +7 more
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Recombination and Its Impact on the Genome of the Haplodiploid Parasitoid Wasp Nasonia [PDF]
, 2010 Homologous meiotic recombination occurs in most sexually reproducing organisms, yet its evolutionary advantages are elusive. Previous research explored recombination in the honeybee, a eusocial hymenopteran with an exceptionally high genome-wide ...
Gibson, Joshua D. +66 more
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Cole1, cer site-specific recombination [PDF]
, 1986 The multicopy, naturally occurring plasmid ColE1 is maintained stably under normal growth conditions, whereas plasmid cloning vectors related to it are relatively unstable.
Stewart, Gillian
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High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells. [PDF]
PLoS ONE, 2007 DNA site-specific recombinases (SSRs) such as Cre, FLPe, and phiC31, are powerful tools for analyzing gene function in vertebrates. While the availability of multiple high-efficiency SSRs would facilitate a wide array of genomic engineering possibilities,
Christopher S Raymond, Philippe Soriano
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Zinc finger recombinases with adaptable DNA sequence specificity [PDF]
, 2011 Site-specific recombinases have become essential tools in genetics and molecular biology for the precise excision or integration of DNA sequences. However, their utility is currently limited to circumstances where the sites recognized by the recombinase ...
Proudfoot, C. +19 more
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