Assembly and activation of site-specific recombination complexes [PDF]
Proceedings of the National Academy of Sciences, 2000 Site-specific recombination is responsible for a broad range of biological phenomena, including DNA inversion, resolution of transposition intermediates, and the integration and excision of bacteriophage genomes. Integration of mycobacteriophage L5 is catalyzed by a phage-encoded integrase with recombination occurring between specific ...
C E, Peña +2 more
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Site-specific recombination caught in the act
Chemistry & Biology, 1997 AbstractThe recently determined crystal structure of Cre recombinase from bacteriophage P1, bound to its target DNA, sheds considerable light on the mechanism underlying a major type of site-specific DNA recombination, and shows how strand exchange can be achieved without reorganisation of the protein complex.
Lilley, David M.J.
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A simplified mathematical model of directional DNA site-specific recombination by serine integrases [PDF]
Journal of the Royal Society Interface, 2017 Alexandra Pokhilko +2 more
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Temporally-controlled site-specific recombination in zebrafish. [PDF]
PLoS ONE, 2009 Conventional use of the site-specific recombinase Cre is a powerful technology in mouse, but almost absent in other vertebrate model organisms. In zebrafish, Cre-mediated recombination efficiency was previously very low.
Stefan Hans +4 more
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Recombination: Pieces of the site-specific recombination puzzle [PDF]
Current Biology, 1995 Understanding how nucleoprotein complexes interact with specific DNA sequences has come closer with structural and mechanistic studies of the interaction between the recombination enzyme resolvase and DNA.
Oram, M., Szczelkun, M.D., Halford, S.E.
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Predicting algorithm of attC site based on combination optimization strategy
Connection Science, 2022 Site-specific recombination systems are widely used as bioengineering tools. However, the traditional site-specific recombination system requires a consensus sequence for the specific site.
Zhendong Liu +9 more
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Attachment site selection and identity in Bxb1 serine integrase-mediated site-specific recombination. [PDF]
PLoS Genetics, 2013 Phage-encoded serine integrases mediate directionally regulated site-specific recombination between short attP and attB DNA sites without host factor requirements.
Shweta Singh +2 more
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Kinetic properties of optogenetic site-specific DNA recombination by LiCre-loxP. [PDF]
Biol OpenDufour A +11 more
europepmc +2 more sources
High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells. [PDF]
PLoS ONE, 2007 DNA site-specific recombinases (SSRs) such as Cre, FLPe, and phiC31, are powerful tools for analyzing gene function in vertebrates. While the availability of multiple high-efficiency SSRs would facilitate a wide array of genomic engineering possibilities,
Christopher S Raymond, Philippe Soriano
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Zinc finger recombinases with adaptable DNA sequence specificity [PDF]
, 2011 Site-specific recombinases have become essential tools in genetics and molecular biology for the precise excision or integration of DNA sequences. However, their utility is currently limited to circumstances where the sites recognized by the recombinase ...
Proudfoot, C. +19 more
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