Results 51 to 60 of about 3,635,491 (290)

Amplification Behaviour of Compressional Waves in Unconsolidated Sediments

Frontiers in Earth Science, 2022
Similar to horizontal earthquake motions, vertical motions are amplified depedent on the local site conditions which can be critical for the safety of certain structures.
Janneke van Ginkel, Janneke van Ginkel, Elmer Ruigrok, Elmer Ruigrok, Rick Wentinck, Rien Herber   +5 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Microtremor Recording Surveys to Study the Effects of Seasonally Frozen Soil on Site Response

Sensors, 2023
Microtremor recording tests using an accelerometer were carried out in this paper with the aim of characterizing the effects of seasonally frozen soil on the seismic site response, including the two-direction microtremor spectrum, site predominant ...
Shengyang Chen, Jie Lei, Ya Li
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Mutations and amplification of oncogenes in endometrial cancer [PDF]

, 1999
Alterations in oncogenes are critical steps in the development of endometrial cancer. To investigate the potential clinical relevance of the amplification of the oncogenes c-erbB2, c-myc, and int-2 and the mutation of K-ras in endometrial cancer, 112 ...
Niederacher, Dieter, Cho, Yong-Jig, An, Han-Xiang, Beckmann, Matthias W., Hantschmann, Peer, Bender, Hans G.   +5 more
core   +1 more source

Seismic risk assessment of architectural heritages in Gyeongju considering local site effects [PDF]

Natural Hazards and Earth System Sciences, 2013
A seismic risk assessment is conducted for cultural heritage sites in Gyeongju, the capital of Korea's ancient Silla Kingdom. Gyeongju, home to UNESCO World Heritage sites, contains remarkable artifacts of Korean Buddhist art.
H.-J. Park, D.-S. Kim, D.-M. Kim
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Impacts of a Moderate-Sized Earthquake: The 2023 Magnitude (M_w) 4.7 Leyte, Leyte Earthquake, Philippines

Geosciences
On 15 January 2023, a shallow, moderate earthquake with a magnitude (Mw) of 4.7 and a depth of one kilometer struck the northern part of Leyte Island in the central Philippines. Originating along the northern Leyte segment of the Philippine Fault, a well-
Jeffrey S. Perez, Deo Carlo E. Llamas, Daniel Jose L. Buhay, Ryan Christian C. Constantino, Crystel Jade M. Legaspi, Kristine Dionne B. Lagunsad, Rhommel N. Grutas, Marc Marion Y. Quimson   +7 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source