Results 71 to 80 of about 418,008 (274)

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

Stability of space use in Svalbard coastal female polar bears: intra-individual variability and influence of kinship

open access: yesPolar Research, 2021
Philopatry influences animal distribution and can lead to a kinship-based spatial structure, where proximity and relatedness are tightly linked. In the Barents Sea region, polar bears (Ursus maritimus) of the coastal ecotype remain year-round within the ...
Clément Brun   +3 more
doaj   +1 more source

Fast Ground State Manipulation of Neutral Atoms in Microscopic Optical Traps

open access: yes, 2005
We demonstrate Rabi flopping at MHz rates between ground hyperfine states of neutral $^{87}$Rb atoms that are trapped in two micron sized optical traps.
D. D. Yavuz   +9 more
core   +1 more source

An engineered Tetrahymena tRNA(Gln) for in vivo incorporation of unnatural amino acids into proteins by nonsense suppression [PDF]

open access: yes, 1996
A new tRNA, THG73, has been designed and evaluated as a vehicle for incorporating unnatural amino acids site-specifically into proteins expressed in vivo using the stop codon suppression technique.
Abelson, John N.   +7 more
core   +1 more source

Testing a Personalized Approach to Chronic Low Back Pain: A Randomized Controlled Trial in Older Veterans

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to test the efficacy of personalized treatment of older veterans with chronic low back pain (CLBP) delivered by Aging Back Clinics (ABCs) as compared with usual care (UC). Methods Two hundred ninety‐nine veterans aged 65 to 89 with CLBP from three Veterans Affairs (VA) medical centers underwent baseline testing, randomization to ABC ...
Debra K. Weiner   +9 more
wiley   +1 more source

Entanglement entropy and fidelity susceptibility in the one-dimensional spin-1 XXZ chains with alternating single-site anisotropy

open access: yes, 2015
We study the fidelity susceptibility in an antiferromagnetic spin-1 XXZ chain numerically. By using the density-matrix renormalization group method, the effects of the alternating single-site anisotropy $D$ on fidelity susceptibility are investigated ...
Liu, Guang-Hua, Ren, Jie, You, Wen-Long
core   +1 more source

Estimating Queen Conch (Strombus gigas) home ranges using acoustic telemetry: implications for the design of marine fishery reserves [PDF]

open access: yes, 2003
Marine reserves (MRs) may function as a vital tool in the conservation and management of marine resources if source populations are managed for the benefit of those downstream.
Delgado, Gabriel A.   +2 more
core   +2 more sources

Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial

open access: yesArthritis Care &Research, EarlyView.
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham   +29 more
wiley   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

open access: yesAdvanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt   +8 more
wiley   +1 more source

Quantum Monte Carlo simulations of fidelity at magnetic quantum phase transitions [PDF]

open access: yes, 2009
When a system undergoes a quantum phase transition, the ground-state wave-function shows a change of nature, which can be monitored using the fidelity concept.
Alet, Fabien   +2 more
core   +2 more sources

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