Results 101 to 110 of about 10,087,786 (356)

Governing electricity in South Africa: wind, coal and power struggles [PDF]

open access: yes, 2011
South Africa’s electricity policy is at a crossroads. Its historical dependence on cheap coal for approximately 90 per cent of its electricity generation is under threat.
Baker, Lucy
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Anatomical Parcellation of Cortical Language Sites [PDF]

open access: yes, 2004
Anatomical labeling of cerebral cortical stimulation (CSM) sites is necessary for intelligent computer querying of a rich and unique experimental database examining neural substrates underlying human language production.
Brinkley, James F   +5 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The tourist map, scientific tool that supports the exploration of protected areas, Bihor County, Romania [PDF]

open access: yesGeoSport for Society, 2016
The study area is a Nature 2000 protected site from Bihor County, Romania. The present study aims at identifying the opportunities for the implementation of a bioeconomic exploitation system, by tourism development, according to its necessities for ...
Grigore Vasile HERMAN   +6 more
doaj  

Comparison Sites [PDF]

open access: yes
Web search technologies are fundamental tools to easily navigate through the huge amount of information available in the Internet. One particular type of search technologies are the so- called shopbots, or comparison sites.
Jose Luis Moraga-Gonzalez   +1 more
core  

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