Results 111 to 120 of about 5,505,675 (308)

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

The tourist map, scientific tool that supports the exploration of protected areas, Bihor County, Romania [PDF]

open access: yesGeoSport for Society, 2016
The study area is a Nature 2000 protected site from Bihor County, Romania. The present study aims at identifying the opportunities for the implementation of a bioeconomic exploitation system, by tourism development, according to its necessities for ...
Grigore Vasile HERMAN   +6 more
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Late Bronze Age settlements in the Visun and the Lower Ingulets rivers basin

open access: yesTyragetia, 2020
This work continues the series of publications on Late Bronze Age sites published in the Tyragetia journal in 2018 and 2019. It significantly complements the archaeological map of the late Bronze Age sites of the Black Sea region.
Victor Grebennikov
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Railway connections and cost thereof in connection with the different proposed Federal Capital Sites [cartographic material] : Map of New South Wales railways ... /

open access: yes, 1904
Map of N.S.W. overprinted in red with proposed Federal Capital Sites (which include Armidale, Bathurst, Orange, Lyndhurst, Tumut, Lake George, Dalgety and Bombala), proposed railways and mileage, with costs.
New South Wales. Department of Lands.
core  

Pogonocaudina indica Sites and Zettel, NEW SPECIES

open access: yes, 2011
Pogonocaudina indica Sites and Zettel, NEW SPECIES Figs. 1, 7, 8 Description. Macropterous male. See generic description; only additional details provided here. Holotype, length 10.50; maximum width 6.13. Paratypes (n = 2), length 10.45–10.56 (mean =
Zettel, Herbert, Sites, Robert W.
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Namtokocoris akekawati Sites, NEW SPECIES

open access: yes, 2007
Namtokocoris akekawati Sites, NEW SPECIES Figs. 3, 5, 10 b, 11 b, 12 b, 13 b, 14 b Descriptions Macropterous male. See generic description; only additional details provided here. Holotype, length 9.46; maximum width 5.98.
Vitheepradit, And Akekawat   +1 more
core   +1 more source

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