Results 61 to 70 of about 1,240 (187)
The Concise Guide to PHARMACOLOGY 2025/26: Transporters
British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +28 more
wiley +1 more source
Post-prandial Remnant Lipoprotein Metabolism in Sitosterolemia
, 2018 Aim: We aimed to clarify post-prandial accumulation of remnant-like particles (RLP) in patients with sitosterolemia. \nMethods: Oral fat tolerance test cream (Jomo Shokuhin, Takasaki, Japan) 50 g was given per body surface area (m2); blood sampling was ...
野村, 章洋 +13 more
core +1 more source
Sitosterolemia caused by mutations in the ABCG8 gene. First case report in Colombia
Revista de la Facultad de Medicina, 2023 Introduction: Sitosterolemia is an autosomal recessive disease caused by mutations in the ABCG5 or ABCG8 genes. It is characterized by reduced excretion of plant sterols and cholesterol, leading to the development of hypercholesterolemia, xanthomas, and ...
Harold Felipe Saavedra-López +2 more
doaj +1 more source
Sitosterolemia, Hypercholesterolemia, and Coronary Artery Disease
, 2018 Sitosterolemia is a rare inherited disease characterized by increased levels of plant sterols, such as sitosterol. The cause of this disease is ATP-binding cassette (ABC) subfamily G member 5 or member 8 (ABCG5 or ABCG8, respectively) gene mutations ...
馬淵, 宏 +10 more
core +1 more source
Oral Fat Tolerance Test for Sitosterolemia and Familial Hypercholesterolemia: A Study Protocol
, 2018 Aim: Sitosterolemia is an extremely rare, autosomal recessive disease characterized by high plasma cholesterols and plant sterols because of increased absorption of dietary cholesterols and sterols from the intestine, and decreased excretion from biliary
野村, 章洋 +9 more
core +1 more source
BAREing it all: the adoption of LXR and FXR and their roles in lipid homeostasis
Journal of Lipid Research, 2002 During the last three years there have been a plethora of publications on the liver X-activated receptors (LXRα, NR1H3, and LXRβ, NR1H2), the farnesoid X-activated receptor (FXR, NR1H4), and the pregnane X receptor (PXR, NR1I2) and the role these nuclear
Peter A. Edwards +2 more
doaj +1 more source
Clinical Case Reports, Volume 12, Issue 2, February 2024.Clinical impact of pharmacotherapy in phenotypic HoFH with large‐scale CNVs deletion in heterozygotes. Key Clinical Message Recent data reveal phenotypic HoFH patients may be responsive to PCSK9 inhibitors, challenging prior assumptions. Genetic testing advancements now more accurately forecast patient responses to these therapies, improving treatment ...
Ryosuke Tani +5 more
wiley +1 more source
, 2017 Severe hypercholesterolemia associated or not with xanthomas in a child may suggest the diagnosis of homozygous autosomal dominant hypercholesterolemia (ADH), autosomal recessive hypercholesterolemia (ARH) or sitosterolemia, depending on the transmission
Francesco Papadia +22 more
core +1 more source