Results 81 to 90 of about 95,199 (265)

Disrupting Colonial Time

open access: yesKvinder, Køn & Forskning
This article explores how Faroese Early Childhood Education and Care (ECEC) both inherits and disrupts colonial temporalities embedded in global education policy.
Greta Jimenez
doaj   +1 more source

Education-based Situated Creativity

open access: yes, 2021
As implied by many and explicitly stated by Florida (2002), „human creativity is the ultimate economic resource.“ However, just like human knowledge, which is one of the preconditions for creativity to occur, creativity does not happen out of thin air. It has its foundations, triggers and constituents.
Bojanjac, Dario   +7 more
openaire   +2 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Application of situated and simulation-based learning technologies in the formation of communication skills in medical students

open access: yesКардиоваскулярная терапия и профилактика
Aim. To improve the effectiveness of the formation of communication skills in medical students by means of situated and simulation-based learning education.Material and methods. A survey of patients was conducted in order to identify the main problems of
E. V. Makaricheva, A. A. Mutigullina
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Education as a mediating interface in global health: A conceptual synthesis of antimicrobial resistance education

open access: yesGlobal Public Health
Often recognised as a determinant of health and key to health communication, education is an underdeveloped concept in global health. This paper develops a conceptual understanding of how educational processes shape engagement with global health ...
Martin Mickelsson, Emma Oljans
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Inclusive musical environments in educational contexts: a conceptual framework for equity, participation, and student wellbeing

open access: yesFrontiers in Psychology
This review develops a framework for examining the conditions under which musical environments may support equity, participation, and situated student wellbeing in educational contexts.
Lorena Alleres-Otero   +4 more
doaj   +1 more source

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