Results 41 to 50 of about 146,579 (266)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Mitificación del desarrollo y mistificación de la cultura: el etnodesarrollo como alternativa [PDF]
Íconos, 2009 Este artículo tiene dos objetivos, el primero develar el contenido ideológico que, desde la academia y desde el “complejo desarrollista”, se ha venido incorporando al concepto de desarrollo.
Pablo Palenzuela Chamorro
doaj
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Critical, Qualitative and Situated: Pedagogical Initiatives in a Datafied Society
SocietiesSocial researchers have extensively examined the systematic role played by digital platforms, algorithms and datafication processes in shaping social life.
Riccardo Pronzato, Ana Kubrusly
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Feminist Epistemologies, Postmodernism, and Critical Pedagogy
Lubelski Rocznik PedagogicznyIntroduction: The debate concerning feminist standpoint epistemology and the concept of situated knowledge represents a crucial moment in the history of contemporary philosophy of education.
Wojciech Kruszelnicki
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Teksty Drugie, 2023 Review: Oskar Szwabowski, Nekrofilna produkcja akademicka i pieśni partyzantów. Autoetnografia pracy akademickiej i dydaktycznej w czasach zombie-kapitalizmu (Necrophilic Academic Production and the Songs of Partisans: Authoethnography of Academic ...
Piotr Juskowiak
doaj
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
International Journal of Education and Practice, 2018 Subconsciously, experienced teachers make use of situated knowledge: knowledge that is connected to, and arises from, the interactions between the physical environment where the action takes place and a material body acting in that environment. Since situated knowledge is important in day-to-day teaching to solve incidents, it should be taught in ...
Walter M Geerts +3 more
openaire +2 more sources