Results 61 to 70 of about 146,886 (264)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Transcultural Dialogue

open access: yesRevista Gearte, 2018
Transcultural Dialogue builds relationships, which becomes the content for a community to create collaborative art based on the group’s dialogue. As an art education professor in the United States, I began facilitating Transcultural Dialogues in 2007 ...
Karen Keifer-Boyd
doaj   +3 more sources

Feminist Epistemologies, Postmodernism, and Critical Pedagogy

open access: yesLubelski Rocznik Pedagogiczny
Introduction: The debate concerning feminist standpoint epistemology and the concept of situated knowledge represents a crucial moment in the history of contemporary philosophy of education.
Wojciech Kruszelnicki
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Critical, Qualitative and Situated: Pedagogical Initiatives in a Datafied Society

open access: yesSocieties
Social researchers have extensively examined the systematic role played by digital platforms, algorithms and datafication processes in shaping social life.
Riccardo Pronzato, Ana Kubrusly
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Sustainability as a Key Outcome: Muisca-Inspired Life Choices in Ráquira, Colombia

open access: yesLand
The United Nations 2030 Agenda often employs universalist metrics that overlook situated territorial ontologies. This study analyzes the Reverdece Association in Ráquira, Colombia, where an evolving self-determined peasant-mestizo family has articulated ...
Jimena Hernández-Parra   +1 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

From situated knowledges to situated modelling: a relational framework for simulation modelling

open access: yesEcosystems and People
In this paper we extend the use of a relational approach to simulation modelling, a widely used knowledge practice in sustainability science. Among modellers, there is awareness that model results can only be interpreted in view of the assumptions that inform model construction and analysis, but less systematic questioning of those assumptions ...
Klein, Anja   +12 more
openaire   +4 more sources

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