Results 101 to 110 of about 34,933 (276)

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Nonavalent HPV vaccine to prevent recurrent anal or vulvar high‐grade squamous intraepithelial lesions (VIVA trial): A randomized, double‐blind, placebo‐controlled trial

International Journal of Cancer, EarlyView.
What's New? Anal and vulvar high‐grade squamous intraepithelial lesions (HSILs) frequently recur following treatment. Additional genital and anal procedures, however, can be distressing for patients and are potentially disfiguring. This trial assessed whether the 9‐valent human papillomavirus (9vHPV) vaccine reduces HSIL recurrence risk or HPV ...
Helen C. Stankiewicz Karita, Amalia S. Magaret, David R. Doody, Jeffrey T. Schouten, Constance Mao, Warner K. Huh, Verena S. Grieco, Matthew A. Seymour, Dana Varon, Kelly H. Shrader, Long Fu Xi, Denise A. Galloway, Anna Wald, Margaret M. Madeleine   +13 more
wiley   +1 more source

Regenerating Gene Protein as a Novel Autoantigen in the Pathogenesis of Sjögren’s Syndrome

Antibodies, 2015
Sjögren’s syndrome, an autoimmune disease characterized by exocrine gland dysfunction leading to dry mouth and dry eye diseases, is typified by lymphoplasmacytic infiltrations and a progressive destruction of the salivary and lacrimal glands.
Takashi Fujimoto, Kiyomi Yoshimoto, Takanori Fujimura, Maiko Takeda, Akiyo Yamauchi, Asako Itaya-Hironaka, Shin Takasawa   +6 more
doaj   +1 more source

Comparison of ESSDAI and ClinESSDAI in potential optimization of trial outcomes in primary Sjögren’s syndrome: examination of data from the UK Primary Sjögren’s Syndrome Registry [PDF]

, 2018
OBJECTIVES: To assess the use of the Clinical EULAR Sjögren’s Syndrome Disease Activity Index (ClinESSDAI), a version of the ESSDAI without the biological domain, for assessing potential eligibility and outcomes for clinical trials in patients with ...
Adrian, J, Alexandre, D, Andrea, R, Annie, C, Benjamin, FA, Bhaskar, D, Bridget, G, Colin, PT, Costantino, P, David, C, David, I, Elizabeth, P, Francesca, B, Ian, G, John, M, Katherine, J, Michele, B, Mohammed, A, Monica, G, Nagui, G, Neil, M, Nurhan, S, Paul, E, Peter, L, Regis, UKPSS, Robert, MJ, Saaeha, R, Simon, BJ, Steven, Y-M, Vadivelu, S, Wan-Fai, N   +30 more
core   +6 more sources

TAM pathway proteins as novel salivary biomarkers for periodontitis

Journal of Periodontology, EarlyView.
Abstract Background The identification of molecular biomarkers that help clinicians in early diagnosis is a key focus of periodontal research. The major aim of this cross‐sectional observational study was to assess whether salivary TAM pathway protein levels have the potential to discriminate between periodontally healthy or gingivitis controls and ...
Karina Mendes, Ana T. P. C. Gomes, Dimitris N. Tatakis, Tiago Marques, Marla Pinto, Pedro C. Lopes, Maria J. Correia, Nuno Rosa   +7 more
wiley   +1 more source

Long‐Term Dermoscopic Evolution of Reticular Erythematous Mucinosis: Case Report

JEADV Clinical Practice, EarlyView.
ABSTRACT Reticular erythematous mucinosis is a rare dermatosis with a challenging diagnosis. To date, its dermoscopic features have not been well characterised in the literature. Only a limited number of case reports have described dermoscopic findings that may be indicative of the disorder, including the presence of dotted and linear vessels, as well ...
Grażyna Kamińska‐Winciorek, Karolina Zarańska, Anastazja Szlauer‐Stefańska, Jacek Pająk, Sebastian Giebel   +4 more
wiley   +1 more source

Effect of Systemic Immunomodulators on Incidence of Alopecia Areata: A Retrospective Cohort Study

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Alopecia areata (AA) is a chronic autoimmune hair loss disorder. Patients with primary autoimmune diseases commonly use systemic immunomodulators to manage disease and have an increased risk of developing AA. Systemic immunomodulators have diverse immunologic effects, but their impact on AA risk is not well understood. Objectives We
Angela Rose Liu, Nada Hentati, Bethany R. Rohr   +2 more
wiley   +1 more source

Handheld spatial frequency domain imager for noninvasive Sjögren's syndrome labial salivary gland biopsy

, 2021
Bixin Zeng, Mingrou Guo, Kangyuan Yu, Li Sun, Weihao Lin, Da Pan, Xiaowei Chen, Min Xu   +7 more
openalex   +1 more source

A Refractory Leg Skin Ulcer Associated With Multiple Myeloma Successfully Treated With Plasma Exchange, Lenalidomide, and Dexamethasone

JEADV Clinical Practice, EarlyView.
ABSTRACT Multiple myeloma (MM) is a malignant plasma cell disorder that primarily presents with CRAB symptoms (calcium elevation, renal failure, anemia, and bone abnormalities). In rare cases, MM manifests with systemic complications like skin ulcers, which present management challenges. Here, we report a 78‐year‐old Japanese man with MM and refractory
Naoko Hattori, Yutaka Kuwatsuka, Tomoka Waseda, Daisuke Ehara, Koji Ando, Hiroyuki Murota   +5 more
wiley   +1 more source

Altered miR‐146a expression in Sjögren's syndrome and its functional role in innate immunity [PDF]

, 2011
Kaleb M. Pauley, Carol Stewart, Adrienne E. Gauna, Lauren C. Dupre, Riya Kuklani, Annie L. Chan, Brad A. Pauley, Westley H. Reeves, Edward K. L. Chan, Seunghee Cha   +9 more
openalex   +1 more source