Results 31 to 40 of about 2,293 (174)
Characterization of Two Distinct Structural Classes of Selective Aldehyde Dehydrogenase 1A1 Inhibitors. [PDF]
, 2015 Aldehyde dehydrogenases (ALDH) catalyze the irreversible oxidation of aldehydes to their corresponding carboxylic acid. Alterations in ALDH1A1 activity are associated with such diverse diseases as cancer, Parkinson?s disease, obesity, and cataracts ...
Hurley, Thomas D., Morgan, Cynthia A.
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Você conhece esta síndrome? Do you know this syndrome?
Anais Brasileiros de Dermatologia, 2010 Relatamos um caso típico, em um paciente masculino de 20 anos, da síndrome de Sjögren-Larsson, que é uma doença neurocutânea, autossômica recessiva e incapacitante, caracterizada por ictiose congênita, plegia espástica e retardo mental.
Marcela Duarte Villela Benez +3 more
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Discovery of a series of aromatic lactones as ALDH1/2-directed inhibitors [PDF]
, 2015 In humans, the aldehyde dehydrogenase superfamily consists of 19 isoenzymes which mostly catalyze the NAD(P)(+)-dependent oxidation of aldehydes.
Buchman, Cameron D. +2 more
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Effects of parabolic flight and spaceflight on the endocannabinoid system in humans [PDF]
, 2012 The endocannabinoid system (ECS) plays an important role in the regulation of physiological functions, from stress and memory regulation to vegetative control and immunity.
Chouker, Alexander +7 more
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Pteridines, 2013 The tetrahydrobiopterin-dependent degradation of ether lipids by alkylglycerol monooxygenase (AGMO) produces fatty aldehydes, which are toxic to cells.
Keller Markus A. +4 more
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Determinants and clinical implications of circulating fatty acids in individuals with chronic kidney disease [PDF]
, 2013 Patients with chronic kidney disease (CKD) have a high risk of cardiovascular morbidity and mortality. Adding to traditional risk factors, e.g., Framingham risk factors, novel risk factors including inflammation, insulin resistance (IR) and metabolic ...
Huang, Xiaoyan
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Reumatismo, 2011 Sjögren-Larsson syndrome (SLS) is an autoimmune disease, uncommon in childhood. We report a case of SLS in a 10-year-old girl with a history of tumor, calor and rubor in the back of her toes almost every month, which resolved in 4-5 days without therapy.
V. Gerloni +4 more
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Small touches to big walks –the impact of rehabilitation on Sjögren-Larsson syndrome: A case report
Journal of Pediatric Rehabilitation Medicine, 2022 Sjögren-Larsson syndrome (SLS) is a rare neurocutaneous disorder characterized by the presence of congenital ichthyosis, spasticity, and mental retardation. As with other rare genetic diseases, treatment is mainly symptomatic.
Gunay Yolcu +3 more
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The Professional Medical Journal, 2006 We present a case report of two brothers suffering from Sjogren-Larsson syndrome, who were bornto consanguineous parents. Sjogren-Larsson syndrome is one of the congenital icthyoses with an autosomal recessiveinheritance . It is characterized by the combination of 1 congenital ichthyosis with spastic diplegia, moderate mentalretardation and retinopathy.
FAWAD MUZAFFAR, MAJID SUHAIL
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Genetic basis of dental agenesis - molecular genetics patterning clinical dentistry [PDF]
, 2013 Tooth agenesis is one of the most common congenital malformations in humans. Hypodontia can either occur as an isolated condition (non-syndromic hypodontia) or can be associated with a syndrome (syndromic hypodontia), highlighting the heterogeneity of ...
Chhabra, Anuj +2 more
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