Results 1 to 10 of about 1,409,170 (188)
Dynamic chromatin accessibility landscape changes following interleukin-1 stimulation
Epigenetics, 2021 Dynamic modifications of chromatin allow rapid access of the gene regulatory machinery to condensed genomic regions facilitating subsequent gene expression. Inflammatory cytokine stimulation of cells can cause rapid gene expression changes through direct
Matt J Barter +9 more
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BMC Musculoskeletal Disorders, 2021 Background Shifts in treatment strategies for rheumatoid arthritis (RA) have made ambulatory care more labour-intensive. These developments have prompted innovative care models, including mobile health (mHealth) applications.
Michaël Doumen +9 more
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Association between Elevated Plasma Homocysteine and Low Skeletal Muscle Mass in Asymptomatic Adults [PDF]
Endocrinology and Metabolism, 2022 Background Homocysteine has been drawing attention with a closed linkage with skeletal muscle. However, the association of hyperhomocysteinemia with decreased skeletal muscle mass remains unclear.
Jae-Hyeong Choi +5 more
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STAR Protocols, 2022 Summary: Advanced techniques combining tissue clearing, deep confocal imaging, and image quantification enable researchers to characterize complex tissue architectures and understand how trauma or disease impact on their respective components.
Nicolas Peredo +5 more
doaj +1 more source
Cost-effectiveness of bringing a nurse into an Italian genetic day clinic: a before and after study
BMC Health Services Research, 2023 Background Only a few studies explore the role of nurses in genetic counselling and genetic health care, and none of them is related to orphan diseases.
Marina Mordenti +7 more
doaj +1 more source
Scientific Reports, 2021 In the field of regenerative medicine, microcarriers are used as support matrix for the growth of adherent cells. They are increasingly recognised as promising biomaterials for large scale, cost-effective cell expansion bioreactor processes.
Sébastien de Bournonville +2 more
doaj +1 more source
PDGF inhibits BMP2-induced bone healing
npj Regenerative Medicine, 2023 Bone regeneration depends on a pool of bone/cartilage stem/progenitor cells and signaling mechanisms regulating their differentiation. Using in vitro approach, we have shown that PDGF signaling through PDGFRβ inhibits BMP2-induced osteogenesis, and ...
Sanja Novak +8 more
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The Key Lnc (RNA)s in Cardiac and Skeletal Muscle Development, Regeneration, and Disease
Journal of Cardiovascular Development and Disease, 2021 Non-coding RNAs (ncRNAs) play a key role in the regulation of transcriptional and epigenetic activity in mammalian cells. Comprehensive analysis of these ncRNAs has revealed sophisticated gene regulatory mechanisms which finely tune the proper gene ...
Amanda Pinheiro, Francisco J. Naya
doaj +1 more source
Cancer Control, 2017 Background Skeletal scintigraphy remains a valuable tool in the initial and subsequent evaluation of the skeletal system in patients with a diagnosis of primary or metastatic neoplasms. Methods We discuss radiopharmaceuticals, nuclear medicine imaging techniques, and current as well as future oncological applications in the adult population.
Jaime L, Montilla-Soler, Rikesh, Makanji
openaire +2 more sources
Glycogenin is Dispensable for Glycogen Synthesis in Human Muscle, and Glycogenin Deficiency Causes Polyglucosan Storage [PDF]
, 2020 Glycogenin is considered to be an essential primer for glycogen biosynthesis. Nevertheless, patients with glycogenin-1 deficiency due to biallelic GYG1 (NM_004130.3) mutations can store glycogen in muscle.
Dellgren, Göran +10 more
core +1 more source