Results 41 to 50 of about 386,289 (317)

Health state utilities for skeletal-related events secondary to bone metastases [PDF]

The European Journal of Health Economics, 2013
Patients with bone metastases often experience skeletal-related events (SREs). Although cost-utility models are used to examine treatments for metastatic cancer, limited information is available on utilities of SREs. The purpose of this study was to estimate the disutility of four SREs: spinal cord compression, pathological fracture, radiation to bone,
Matza, L.S., Chung, K., Van Brunt, K., Brazier, J.E., Braun, A., Currie, B., Palsgrove, A., Davies, E., Body, J.-J.   +8 more
openaire   +4 more sources

Palaeobiology of Pliocene-Pleistocene shallow-water biocalcarenites (Northern Apennines, Italy) and their relationship with coeval sapropels [PDF]

, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Cau, S., Roveri, M., & Taviani, M.
Cau, Simone, Roveri, Marco, Taviani, Marco   +2 more
core   +1 more source

Risk of skeletal related events among elderly prostate cancer patients by site of metastasis at diagnosis

Cancer Medicine, 2016
The purpose of this study was to estimate the risk of developing skeletal‐related events (SREs) based on site of metastasis at diagnosis and identify other predictors of developing SREs among metastatic prostate cancer patients.
Arif Hussain, Abdalla Aly, C. Daniel Mullins, Yi Qian, Jorge Arellano, Eberechukwu Onukwugha   +5 more
doaj   +1 more source

Skeletal-Related Events due to Bone Metastases from Differentiated Thyroid Cancer [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2012
In oncology, the clinical impact of metastatic bone disease is conveyed via a composite end point termed skeletal-related events (SRE), which encompasses spinal cord compression, pathological fracture, a need for external beam radiation or surgery to bone, and hypercalcemia of malignancy.
Azeez, Farooki, Vivien, Leung, Hernan, Tala, R Michael, Tuttle   +3 more
openaire   +2 more sources

Tahiti sea level : the last deglacial sea level rise in the South Pacific [PDF]

, 2005
Integrated Ocean Drilling Program (IODP) Expedition 310 to the reef terraces around Tahiti, French Polynesia, was the second expedition to utilize a mission-specific platform (MSP) and was conducted by the European Consortium for Ocean Research Drilling (
Camoin, Gilbert F., Iryu, Yasufumi, McInroy, David   +2 more
core   +1 more source

Current comprehensive understanding of denosumab (the RANKL neutralizing antibody) in the treatment of bone metastasis of malignant tumors, including pharmacological mechanism and clinical trials

Frontiers in Oncology, 2023
Denosumab, a fully humanized monoclonal neutralizing antibody, inhibits activation of the RANK/RANKL/OPG signaling pathway through competitive binding with RANKL, thereby inhibiting osteoclast-mediated bone resorption.
Junjie Lu, Desheng Hu, Yan Zhang, Chen Ma, Lin Shen, Bo Shuai   +5 more
doaj   +1 more source

Impact of exercise-nutritional state interactions in patients with type 2 diabetes

, 2020
Introduction This study examines the role of nutritional status during exercise training in patients with type 2 diabetes mellitus by investigating the effect of endurance-type exercise training in the fasted versus the fed state on clinical outcome ...
Calders, Patrick, Celie, Bert, Dendale, Paul, Hansen, Dominique, Lapauw, Bruno, Stevens, An, van Loon, Luc JC, Vandenabeele, Frank, Verboven, Kenneth, Wens, Inez   +9 more
core   +1 more source

The prevalence and risks of injury for masters athletes : current findings [PDF]

, 2015
textRegular physical activity and exercise are important clinical tools that can be used to improve our health. This is especially true due to the prolonged lifespan of the average adult and the declines in physical function that are attributed to ...
Baker, Jeffrey Robinson
core   +1 more source

Are bone targeted agents still useful in times of immunotherapy? The SAKK 80/19 BTA pilot study

Bone Reports
Background: Patients with bone metastases from solid tumors often have additional treatment with bone targeted agents (BTAs) to avoid symptomatic skeletal events (SSEs) such as clinically significant pathological fracture leading toradiation therapy or ...
Michael Mark, Alfonso Rojas Mora, Thomas Winder, Anastasios Stathis, Andreas Jakob, Gisela Müller, Stefanie Hayoz, Patrick Reimann, Ulf Petrausch, Roger von Moos   +9 more
doaj   +1 more source

The pattern of bone involvement, management, and outcomes in patients with nonsmall cell lung cancer: A retrospective study

Annals of Thoracic Medicine, 2018
CONTEXT AND AIM: The skeleton is a frequent site for metastasis in patients with breast, lung, and prostate cancer. Bone metastasis compromises skeletal integrity leading to skeletal-related events (SREs).
Abdulrahman M Jazieh, Thuraya S AlSumai, Yosra Z Ali, Nagham R Sheblaq, Mohammad Alkaiyat   +4 more
doaj   +1 more source