Prevalence of skeletal-related events in hormone-naive prostate cancer in a low resource setting
Background: Presentation with symptoms of advanced prostate cancer is prevalent in developing societies. The objective of this study was to determine the rate of and factors associated with skeletal-related events (SREs) at presentation with hormone ...
Fredrick Obiefuna Ugwumba +5 more
doaj +1 more source
Study of calcium sparks in skeletal and smooth muscle cells in normal and pathological conditions [PDF]
mTOR signaling influence a wide range of cellular process including protein synthesis (Iadevaia et al., 2012; Ma and Blenis, 2009; Thoreen et al., 2012), lipids synthesis (Lamming and Sabatini, 2013), transcription (Dibble and Manning, 2013; Vazquez ...
López, Rubén
core +1 more source
Complications of bone metastases from malignant melanoma
Introduction: Metastatic bone disease (MBD) carries significant morbidity for patients with cancer. MBD from malignant melanoma (MM) is understudied. We examined the characteristics, morbidity, management and outcome of MBD in patients with MM.
Jamal Zekri +5 more
doaj +1 more source
BACKGROUND International guidelines state that bone-targeted agents such as denosumab or zoledronic acid at doses used for bone metastasis are not indicated for patients with metastatic castration-sensitive prostate cancer (mCSPC) with bone ...
Sandro T. Stoffel +13 more
doaj +1 more source
Bisphosphonates in oncology: evidence for the prevention of skeletal events in patients with bone metastases [PDF]
Thomas J PolascikDivision of Urology, Department of Surgery, Duke University Medical Center, Durham, NC, USAAbstract: Bone metastases frequently occur in patients with advanced solid tumors, particularly breast and prostate cancers, and nearly all ...
Thomas J Polascik, Thomas Polascik
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Supplemental Tables: Factors Associated with Skeletal-Related Events in Patients with Bone Metastatic Melanoma: A Retrospective Study of 481 Patients [PDF]
The following supplemental tables are for the benefit of the reviewers only.Supplemental Table 1. Patient baseline characteristics comparing patients with and without the occurrence of skeletal-related events throughout the study period.
Shimizu, M (via Mendeley Data)
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Skeletal-Related Events (SRE) in Prostate Cancer: A Report of Two Cases
A skeletal-related event (SRE) is an event occurring due to bone metastasis in prostate cancer. SREs are usually marked by pain, pathological fractures, spinal cord compression, hypercalcemia, or bone metastasis requiring radiotherapy or operation.
Anak Agung Ngurah Oka Diatmika +1 more
doaj +1 more source
Bone health and therapeutic agents in advanced prostate cancer
Prostate cancer is the most frequent genitourinary tumor worldwide. Maintaining an optimum bone health throughout the natural course of prostate cancer is an important aspect in the management of this disease, particularly in this at risk population of ...
Maria Antonia Gómez-Aparicio +11 more
doaj +1 more source
Regulation of skeletal muscle cell plasticity by the peroxisome proliferator-activated receptor gamma coactivator 1alpha [PDF]
Exercise triggers a pleiotropic response in skeletal muscle, which results in a profound remodeling of this tissue. Physical activity-dependent muscle fiber plasticity is regulated by a number of distinct signaling pathways.
Handschin, C.
core +1 more source
Percentage of skeletal-related events (SREs) occurring in patients with bone metastases from gastric cancer. [PDF]
Percentage of skeletal-related events (SREs) occurring in patients with bone metastases from gastric cancer.
Saverio Cinieri (477380) +28 more
core +1 more source

