Results 41 to 50 of about 472,035 (296)

Do metastatic volumes measured in breast cancer patients with bone metastases correlate with the numbers of skeletal and extraskeletal events? [PDF]

Objectives: The study aimed to investigate the relationship between metastatic volume measurement, skeletal-related events, and survival in women diagnosed with breast cancer and bone metastases.
Yagar, Hilal, Ozturk, Recep, Dede, Didem Sener, Aytekin, Mahmut Nedim, Sendur, Mehmet Ali Nahit, Yalcin, Buelent   +5 more
core   +1 more source

Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. I - Regulation of myogenesis and environmental impact [PDF]

, 2010
Skeletal muscle development in vertebrates – also termed myogenesis – is a highly integrated process. Evidence to date indicates that the processes are very similar across mammals, poultry and fish, although the timings of the various steps differ ...
Wimmers, K, Nottingham, Te Pas, M. F. W., N. Oksbjerg, Te Pas, M. F.W., Stickland, N C, Algarve, Rehfeldt, C., Stickland, Neil, Rehfeldt, Charlotte, Oksbjerg, Niels, Brameld, J M, Picard, Brigitte, B., Te Pas, Marinus, Pas, M, Nissen, P M, Power, D M, Valente, L M P, K. Wimmers, Oksbjerg, N, Nissen, Pia, Wimmers, Klaus, Valente, L.M.P., Brameld, J. M., Leibniz Institute For Farm Animals, M.F.W. Te Pas, Picard, B., Stickland, N.C., Pas, M.F.W., te, Berri, C., Picard, B, Nissen, P. M., B. Picard, Stickland, N. C., Berri, C, Rehfeldt, C, P.M. Nissen, Valente, L. M.P., Valente, Luísa, Power, Deborah, Wageningen UR, The Netherlands, Brameld, John, INRA, France, Nissen, P.M., te Pas, M.F.W., Brameld, J.M., Aarhus, C. Rehfeldt, Wimmers, K., N.C. Stickland, Power, D. M., C. Berri, D.M. Power, Valente, L. M. P., J.M. Brameld, Power, D.M., L.M.P. Valente, Berri, Cécile, Porto, Oksbjerg, N.   +59 more
core   +1 more source

Skeletal-related events (SREs) are common in patients with bone metastasis from renal cell carcinoma (N = 398). [PDF]

, 2013
Skeletal-related events (SREs) are common in patients with bone metastasis from renal cell carcinoma (N = 398).
Saverio Cinieri (477380), Sergio Bracarda (503257), Nicola Silvestris (477360), Giuseppe Badalamenti (503251), Sandro Barni (477365), Giuseppe Tonini (222938), Rossana Berardi (477376), Vincenzo Adamo (503254), Calogero Mazzara (503245), Giacomo Carteni (5657380), Andrea Fontana (152789), Francesca Maria Tanca (503253), Roberto Sabbatini (503255), Maria Antonietta Satolli (477367), Evaristo Maiello (477372), Daniele Santini (222870), Matteo Santoni (503249), Camillo Porta (133354), Stefano Luzi Fedeli (503252), Gaetano Lanzetta (503247), Alfredo Berruti (503246), Cinzia Ortega (222881), Giuseppe Procopio (503244), Toni Ibrahim (477361), Davide Ottaviani (23156), Elena Collovà (503250), Vladimir Virzì (503248), Antonio Russo (168018), Alessandra Felici (503256), Bruno Vincenzi (82033)   +29 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Incidence of skeletal-related events (SREs) in patients with bone metastases from renal cell carcinoma (N = 398). [PDF]

, 2013
Incidence of skeletal-related events (SREs) in patients with bone metastases from renal cell carcinoma (N = 398).
Saverio Cinieri (477380), Sergio Bracarda (503257), Nicola Silvestris (477360), Giuseppe Badalamenti (503251), Sandro Barni (477365), Giuseppe Tonini (222938), Rossana Berardi (477376), Vincenzo Adamo (503254), Calogero Mazzara (503245), Giacomo Carteni (5657380), Andrea Fontana (152789), Francesca Maria Tanca (503253), Roberto Sabbatini (503255), Maria Antonietta Satolli (477367), Evaristo Maiello (477372), Daniele Santini (222870), Matteo Santoni (503249), Camillo Porta (133354), Stefano Luzi Fedeli (503252), Gaetano Lanzetta (503247), Alfredo Berruti (503246), Cinzia Ortega (222881), Giuseppe Procopio (503244), Toni Ibrahim (477361), Davide Ottaviani (23156), Elena Collovà (503250), Vladimir Virzì (503248), Antonio Russo (168018), Alessandra Felici (503256), Bruno Vincenzi (82033)   +29 more
core   +1 more source

The effects of daratumumab on bone disease in patients with newly diagnosed multiple myeloma: a multi-center retrospective study

BMC Cancer
Background Daratumumab (Dara), a humanized IgGκ monoclonal antibody targeting CD38, has shown significant efficacy in the treatment of multiple myeloma (MM).
Xinrong Li, Hua Wang, Yizhen Li, Jing Zhou, Nianhui Yang, Xiaolei Wei, Xiangran Cai, Zeyu Xiao, Juan Du, Hui Zeng   +9 more
doaj   +1 more source

Managing Bone Metastases with Denosumab: Real-World Data and Critical Monitoring Points in Breast, Lung, and Prostate Cancers

Medicina
Background and Objectives: Advanced solid organ tumors, particularly breast, lung, and prostate cancers, frequently metastasize to bone, leading to debilitating skeletal-related events (SREs).
Sibel Oyucu Orhan, Bedrettin Orhan, Şeyma Esenbuğa, Seda Sali, Burcu Caner, Birol Ocak, Ahmet Bilgehan Şahin, Adem Deligönül, Türkkan Evrensel, Erdem Çubukçu   +9 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Current comprehensive understanding of denosumab (the RANKL neutralizing antibody) in the treatment of bone metastasis of malignant tumors, including pharmacological mechanism and clinical trials

Frontiers in Oncology, 2023
Denosumab, a fully humanized monoclonal neutralizing antibody, inhibits activation of the RANK/RANKL/OPG signaling pathway through competitive binding with RANKL, thereby inhibiting osteoclast-mediated bone resorption.
Junjie Lu, Desheng Hu, Yan Zhang, Chen Ma, Lin Shen, Bo Shuai   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source