Results 1 to 10 of about 383,968 (297)

Preventing Skeletal-Related Events in Newly Diagnosed Multiple Myeloma [PDF]

Cells
Despite the increasing number of novel therapies to treat newly diagnosed multiple myeloma (NDMM), preventing skeletal-related events (SREs) remains a challenge.
Benjamin Massat, Patrick Stiff, Fatema Esmail, Estefania Gauto-Mariotti, Patrick Hagen   +4 more
doaj   +4 more sources

Experience with denosumab (XGEVA®) for prevention of skeletal-related events in the 10 years after approval [PDF]

Journal of Bone Oncology, 2022
Skeletal-related events (SREs) are complications of bone metastases and carry a significant patient and economic burden. Denosumab is a receptor activator of nuclear factor-κB ligand (RANKL) inhibitor approved for SRE prevention in patients with multiple
Benoit Cadieux, Robert Coleman, Pegah Jafarinasabian, Allan Lipton, Robert Z. Orlowski, Fred Saad, Giorgio V. Scagliotti, Kazuyuki Shimizu, Alison Stopeck   +8 more
doaj   +4 more sources

The importance of retaining physical functions to prevent skeletal‐related events in multiple myeloma patients with bone disease [PDF]

eJHaem, 2022
This study was undertaken to identify baseline conditions and triggering factors for skeletal‐related events (SRE) in multiple myeloma (MM) patients treated with denosumab.
Hirokazu Miki, Shingen Nakamura, Masahiro Oura, Masafumi Nakamura, Ryohei Sumitani, Kimiko Sogabe, Mamiko Takahashi, Tomoko Maruhashi, Takeshi Harada, Shiro Fujii, Hirofumi Hamano, Masateru Kondo, Naoto Okada, Itsuro Endo, Masahiro Abe   +14 more
doaj   +2 more sources

Incidence, Risk Factors, and Survival of Bone Metastases and Skeletal-Related Events in Melanoma Patients: A Systematic Review and Quality Assessment of 29 Studies [PDF]

Journal of Bone Oncology
Background: Skeletal metastases make up 17% of all metastases from advanced-stage melanoma. Bone metastases are associated with increased morbidity and mortality and decreased quality of life due to their association with skeletal-related events (SREs ...
Michelle R. Shimizu, Olaf N. van de Langerijt, Daniel Torres, Tom M de Groot, Olivier Q. Groot   +4 more
doaj   +2 more sources

Clinicopathologic characteristics, metastasis-free survival, and skeletal-related events in 628 patients with skeletal metastases in a tertiary orthopedic and trauma center [PDF]

World Journal of Surgical Oncology, 2021
Background Skeletal-related events (SREs) due to bone metastases (BM) significantly impact the morbidity and mortality of cancer patients. The present study sought to investigate clinicopathological characteristics, metastasis-free survival (MFS), and ...
Georg Herget, Babak Saravi, Eugenia Schwarzkopf, Mara Wigand, Norbert Südkamp, Hagen Schmal, Markus Uhl, Gernot Lang   +7 more
doaj   +2 more sources

BONE METASTATIC DISEASE AND SKELETAL RELATED EVENTS – national recommendations

Zdravniški Vestnik, 2014
The national recommendations for bone metastatis disease, diagnostics and treatment options were defined at the interdisciplinary consensus meeting of basic scientists and clinicans.
Radko Komadina, Marko Špiler, Klemen Grabljevec, Marko Snoj   +3 more
doaj   +1 more source

Bone Metastases and Skeletal-Related Events in Medullary Thyroid Carcinoma.

J Clin Endocrinol Metab, 2016
Bone metastases (BM) can lead to devastating skeletal-related events (SREs) in cancer patients. Data regarding medullary thyroid carcinoma (MTC) with BM are lacking.We evaluated the natural history of BM and SREs in MTC patients identified by a cancer center tumor registry.The study was conducted at a tertiary cancer center.We retrospectively reviewed ...
Xu JY, Murphy WA, Milton DR, Jimenez C, Rao SN, Habra MA, Waguespack SG, Dadu R, Gagel RF, Ying AK, Cabanillas ME, Weitzman SP, Busaidy NL, Sellin RV, Grubbs E, Sherman SI, Hu MI.   +16 more
europepmc   +4 more sources

Bone metastases from head and neck malignancies: Prognostic factors and skeletal-related events. [PDF]

PLoS ONE, 2019
BackgroundWe conducted a multicenter retrospective analysis to describe the characteristics, frequency of skeletal-related events (SREs), and prognosis of head and neck cancer (HNC) in patients with bone metastases (BM).Patients and methodsThe data of ...
Salvatore Grisanti, Susanna Bianchi, Laura D Locati, Luca Triggiani, Stefania Vecchio, Alberto Bonetta, Cristiana Bergamini, Pierfranco Conte, Mario Airoldi, Marco Merlano, Paolo Carlini, Toni Ibrahim, Ciro Rossetto, Salvatore Alfieri, Paolo Pronzato, Sandro Tonoli, Roberto Maroldi, Piero Nicolai, Carlo Resteghini, Stefano M Magrini, Alfredo Berruti   +20 more
doaj   +2 more sources

Bone metastases and skeletal-related events from neuroendocrine tumors [PDF]

Endocrine Connections, 2015
Neuroendocrine tumors (NETs) metastasize to bone; however, a multi-institution evaluation of the natural history and complications of bone metastases across multiple NET subtypes has not, to our knowledge, previously been conducted. At two tertiary academic centers, we identified patients with bone metastases from databases of patients with a diagnosis
Van Loon, Katherine, Zhang, Li, Keiser, Jennifer, Carrasco, Cendy, Glass, Katherine, Ramirez, Maria-Teresa, Bobiak, Sarah, Nakakura, Eric K, Venook, Alan P, Shah, Manisha H, Bergsland, Emily K   +10 more
openaire   +4 more sources

Pain and analgesic use associated with skeletal-related events in patients with advanced cancer and bone metastases [PDF]

, 2005
PURPOSE: Bone metastases secondary to solid tumors increase the risk of skeletal-related events (SREs), including the occurrence of pathological fracture (PF), radiation to bone (RB), surgery to bone (SB), and spinal cord compression (SCC).
Roger von Moos, Jean-Jacques Body, Blair Egerdie, Alison Stopeck, Janet Brown, Lesley Fallowfield, Donald L. Patrick, Charles Cleeland, Danail Damyanov, Felipe Salvador Palazzo, Gavin Marx, Ying Zhou, Ada Braun, Arun Balakumaran, Yi Qian, RE Coleman, RE Coleman, R Moos von, S Vadhan-Raj, GR Mundy, GD Roodman, JA Ford, A Lipton, F Saad, LS Rosen, L Costa, CS Cleeland, K Lemay, CS Cleeland, M Maltoni, L Costa, CS Cleeland, R Moos von, L Costa, AT Stopeck, K Fizazi, DH Henry, D Henry, GV Scagliotti, A Lipton, CS Cleeland, KC Chung, DF Cella, K Webster, N Sathiakumar, N Sathiakumar, K Fizazi, M Yong, M Norgaard, K Cetin, C Nieder, E Chow, MR Smith, A Hussain, AM Abdulhalim, G Oster   +55 more
core   +5 more sources