Results 71 to 80 of about 1,413,705 (310)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Infanticide in Chimpanzees: Taphonomic Case Studies from Gombe [PDF]
, 2017 Objectives We present a study of skeletal damage to four chimpanzee (Pan troglodytes) infanticide victims from Gombe National Park, Tanzania. Skeletal analysis may provide insight into the adaptive significance of infanticide by examining whether ...
Collins, D. Anthony +5 more
core +2 more sources
Donald School Journal of Ultrasound in Obstetrics and Gynecology, 2011 ABSTRACT The word dysplasia originates from the ancient Greek words dys (anomalous) and plasia (formation). Skeletal dysplasia (SD) is a heterogeneous group of congenital anomalies characterized by abnormalities in the development of bone and cartilage tissues.
Antsaklis, A., Anastasakis, E.
openaire +2 more sources
Welcome to Skeletal Muscle [PDF]
Skeletal Muscle, 2011 Over the past decade or two, cellular signaling and molecular genetics have combined to allow for a tremendous increase in the understanding of fundamental processes that are distinct to skeletal muscle: the genes that initiate its differentiation from progenitor cells and which establish its identity; pathways that are responsible for its hypertrophy ...
Glass David J +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies
Bone ResearchSclerosteosis, an ultra-rare disorder characterised by high bone mass (HBM) and skeletal overgrowth, leads to facial paralysis, hearing loss and raised intracranial pressure, which is currently managed only through high-risk surgery.
Timothy J. Dreyer +7 more
doaj +1 more source
A rare phenomenon of twin spotting: Phacomatosis pigmentokeratotica
Indian Journal of Paediatric Dermatology, 2019 Phacomatosis pigmentokeratotica is a rare form of cutaneous mosaicism characterized by epidermal nevus usually nevus sebaceous, papular speckled lentiginous nevus, and extracutaneous anomalies.
Vaishali Wankhade +3 more
doaj +1 more source
Faunal Remains from Shikarpur, a Harappan Site in Gujarat, India [PDF]
Iranian Journal of Archaeological Studies, 2011 This paper deals with the preliminary observations of the analysis conducted on the faunal remains unearthed at thesite of Shikarpur. A single trench ES4 was selected as a research sample from the excavation conducted by theDepartment of Archaeology and ...
Pramod Joglekar, Pankaj Goyal
doaj +1 more source
Immunostaining of skeletal tissues [PDF]
, 2011 Peer ...
De Bari, Cosimo, Kurth, Tobias B
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source