Results 61 to 70 of about 1,413,705 (310)

Skeletal semantics and their interpretations [PDF]

Proceedings of the ACM on Programming Languages, 2019
The development of mechanised language specification based on structured operational semantics, with applications to verified compilers and sound program analysis, requires huge effort. General theory and frameworks have been proposed to help with this effort.
Bodin, Martin, Gardner, Philippa, Jensen, Thomas, Schmitt, Alan   +3 more
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Clinical Impact of Cachexia in Head and Neck Cancer Patients Who Received Chemoradiotherapy

Cancer Management and Research, 2021
Naomi Hayashi,1 Yasuyoshi Sato,1 Yu Fujiwara,1,2 Naoki Fukuda,1 Xiaofei Wang,1 Kenji Nakano,1 Testuya Urasaki,1 Akihiro Ohmoto,1 Makiko Ono,1 Junichi Tomomatsu,1 Yukiko Sato,3 Hiroki Mitani,4 Takashi Toshiyasu,5 Shunji Takahashi1 1Department of Medical ...
Hayashi N, Sato Y, Fujiwara Y, Fukuda N, Wang X, Nakano K, Urasaki T, Ohmoto A, Ono M, Tomomatsu J, Sato Y, Mitani H, Toshiyasu T, Takahashi S   +13 more
doaj  

n-3 essential fatty acid and vitamin D supplementation improve skeletal health in laying hens

Poultry Science, 2023
: Keel bone fractures and osteoporosis are prevalent and damaging skeletal issues in the laying hen industry. There is a large interest in improving bone quality parameters to reduce or eliminate these conditions, thus improving bird welfare.
Meagan E. Abraham, Cara I. Robison, Woo K. Kim, Prafulla Regmi, Darrin M. Karcher   +4 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Isometric hip muscle strength in posttraumatic below-knee amputees [PDF]

Vojnosanitetski Pregled, 2007
Background/Aim. Traumas and war injuries, next to chronic occlusive artery disease and diabetes mellitus-derived complications, are the most frequent cause of the lower limbs amputation.
Jandrić Slavica
doaj   +1 more source

Nitric oxide synthase in skeletal muscle fibres of patients with type 2 diabetes [PDF]

, 2012
Muscle-derived nitric oxide (NO) mediates fundamental physiological actions on skeletal muscle including glucose uptake into muscle cells. Recently, we have shown that the altered glucose metabolism in skeletal muscle of patients with type 2 diabetes ...
Andreas Oberbach, Igor Buchwalow, Karla Punkt, Katharina Kandt, Matthias Blueher, Volker Adams   +5 more
core   +1 more source

Body size, skeletal maturity and functional characteristics of elite academy soccer players on entry between 1992 and 2003 [PDF]

, 2012
Secular changes in body size, estimated fatness, skeletal maturation, and functional characteristics of youth soccer players on entry into an elite academy between 1992 and 2003 were compared.
Carling, C., Le Gall, F.,, Malina, R.M.
core   +1 more source

Skeletal Structures

, 2008
Shape Descriptors are compact and expressive representations of objects suitable for solving problems like recognition, classification, or retrieval of shapes, tasks that are computationally expensive if performed on huge data sets. Skeletal structures are a particular class of shape descriptors, which attempt to quantify shapes in ways that agree with
Biasotti S, DAttali, Boissonnat JD, Edelsbrunner H, Elber G, Mortara M, Sanniti di Baja G, Spagnuolo M, Tanase M, Veltkamp R   +9 more
openaire   +4 more sources