Results 61 to 70 of about 973,362 (309)

Skeletal semantics and their interpretations [PDF]

open access: yesProceedings of the ACM on Programming Languages, 2019
The development of mechanised language specification based on structured operational semantics, with applications to verified compilers and sound program analysis, requires huge effort. General theory and frameworks have been proposed to help with this effort.
Bodin, Martin   +3 more
openaire   +3 more sources

Mouse skeletal muscle fiber-type-specific macroautophagy and muscle wasting are regulated by a Fyn/STAT3/Vps34 signaling pathway [PDF]

open access: yes, 2012
Skeletal muscle atrophy induced by aging (sarcopenia), inactivity, and prolonged fasting states (starvation) is predominantly restricted to glycolytic type II muscle fibers and typical spares oxidative type I fibers.
Bastie, Claire C.   +12 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Entanglement of Skeletal Regions

open access: yesPhysical Review Letters, 2022
5+8 pages, 3+2 figures; v2: discussion and presentation of our results improved; v3: match published ...
Clément Berthiere   +1 more
openaire   +3 more sources

Skeletal abnormalities of acrogeria, a progeroid syndrome [PDF]

open access: yes, 1987
We report the skeletal abnormalities in a 4 1/2-year-old boy with acrogeria, a progeroid syndrome of premature aging of the skin without the involvement of internal organs seen in Hutchinson-Gilford progeria syndrome.
A. Ho   +5 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Welcome to Skeletal Muscle [PDF]

open access: yesSkeletal Muscle, 2011
Over the past decade or two, cellular signaling and molecular genetics have combined to allow for a tremendous increase in the understanding of fundamental processes that are distinct to skeletal muscle: the genes that initiate its differentiation from progenitor cells and which establish its identity; pathways that are responsible for its hypertrophy ...
Glass David J   +2 more
openaire   +3 more sources

Effect of carnitine, acetyl-, and propionylcarnitine supplementation on the body carnitine pool, skeletal muscle composition, and physical performance in mice [PDF]

open access: yes, 2014
Pharmacokinetics and effects on skeletal muscle and physical performance of oral acetylcarnitine and propionylcarnitine are not well characterized. We therefore investigated the influence of oral acetylcarnitine, propionylcarnitine, and carnitine on body
Morand, Réjane   +6 more
core   +1 more source

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