Results 231 to 240 of about 965,762 (355)

Making sense of MYC in skeletal muscle: location, duration, and magnitude. [PDF]

Am J Physiol Cell Physiol
Jones RG, Edman S, Serrano N, Wen Y, McCarthy JJ, Fry CS, von Walden F, Murach KA.   +7 more
europepmc   +1 more source

HMGB2 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through MTA2‐Driven Metabolic Reprogramming

Advanced Science, EarlyView.
In contrast to the adult mammalian heart, which lacks regenerative capacity, the neonatal heart retains a transient regenerative capacity. In this study, high mobility group box 2 (HMGB2) is identified as a crucial protein driving heart regeneration based on comprehensive analyses using quantitative proteomics with tandem mass tag (TMT) labelling, RNA ...
Liu‐Hua Zhou, Ling‐Feng Gu, Yi‐Xi Chen, Peng Jing, Tong‐Tong Yang, Ye He, Yu‐Lin Bao, Xiang‐Zheng Zhang, Chong Du, Si‐Bo Wang, Tian‐Kai Shan, Jia‐Yi Chen, Hao Wang, Qi‐Ming Wang, Li‐Ping Xie, Yang Zhao, Yong Ji, Lian‐Sheng Wang   +17 more
wiley   +1 more source

A characterization of dynamic resistance training-induced skeletal muscle adaptations in hypertensive rats. [PDF]

Physiol Rep
de Araujo AA, Dias DDS, Alves AN, Bernardes N, Curi R, Damaceno-Rodrigues NR, Caldini EG, Ferreira-Mesquita RA, Irigoyen MC, De Angelis K.   +9 more
europepmc   +1 more source

Muscle Organoids Reveal Exercise‐Like Contractions Rapidly Promote Muscle Health Via Lamtor1's Signaling to Both AMPK and mTOR

Advanced Science, EarlyView.
This study develops a novel 3D human skeletal muscle organoid platform to study the immediate molecular effects of exercise‐like contractions. The model uncovers rapid proteomic and transcriptomic responses, resolving a fundamental paradox by demonstrating how exercise‐induced Lamtor1 coordinately activates both AMPK and mTORC1. Lamtor1 is a compelling
Ziyue Yao, Zongmin Jiang, Xupeng Liu, Liping Zhang, Siyu Guo, Yu Chen, Lanfang Luo, Shilin Ma, Peng Wang, Ng Shyh‐Chang   +9 more
wiley   +1 more source

Metabolic and molecular regulation in skeletal muscle dysfunction and regeneration. [PDF]

Front Cell Dev Biol
Jin JB, Robinson A, Soukup T, Black E, Abit A, Hammer SM, Han A, Lucas E, Kim Y, Bae J.   +9 more
europepmc   +1 more source

A Herbal‐Piezoelectric Heterojunction Strategy to Potentiate Bacterial Cuproptosis‐Like Death and Remodel the Inflammatory Microenvironment in Infection‐Associated Implant Osteomyelitis

Advanced Science, EarlyView.
A titanium implant coating integrating berberine and copper‐doped strontium titanate leverages ultrasound to compromise bacterial membranes and induce cuproptosis‐like death. This approach resolves S. aureus infections in osteomyelitis models while suppressing inflammation and promoting osseointegration, demonstrating a dual‐functional strategy against
Guannan Zhang, Zehao Li, Ying Lu, Jianbo Song, Xingyu Liang, Peide Han, Xiaohong Yao, Yongqiang Yang, Xiangyu Zhang   +8 more
wiley   +1 more source

Insights into WDR5: unveiling its functions, regulation, and impact on skeletal muscle. [PDF]

Epigenetics
Bahena-Culhuac E, Hernández-Somilleda M, Hernández-Hernández JM.   +2 more
europepmc   +1 more source

Effect of denervation and cocainization on the activity of creatine synthesing enzyme and phosphorylase in the skeletal muscle

, 1959
Takashi Matsui
openalex   +2 more sources

TWF2 Drives Tumor Progression and Sunitinib Resistance in Renal Cell Carcinoma through Hippo Signaling Suppression

Advanced Science, EarlyView.
Twinfilin actin‐binding protein (TWF2) is upregulated in sunitinib‐resistant renal cell carcinoma (RCC) cells, where it interacts with YAP and protects YAP from degradation. Stabilized YAP translocates into the nucleus and activates transcription of target genes, promoting RCC progression and drug resistance.
Liangmin Fu, Wuyuan Liao, Youyan Tan, Hansen Lin, Kun Ye, Xinwei Zhou, Mingjie Lin, Kangbo Huang, Minyu Chen, Jietao Wei, Haoqian Feng, Yuhang Chen, Jinwei Chen, Bohong Guan, Shan Li, Zhengkun Zhang, Anze Yu, Zihao Feng, Lizhen Zhang, Guannan Shu, Jun Lu, Wei Chen, Yihui Pan, Jiefeng Yang, Junhang Luo, Li Luo   +25 more
wiley   +1 more source

Mechanomedicine for Addressing Skeletal Muscle Insulin Resistance.

Endocr Rev
Wang L, Chang L, Ma Y, Jia Y, Gao B, Cui W, Xu F.   +6 more
europepmc   +1 more source