Results 231 to 240 of about 2,563,441 (411)
CRISPR/Cas9, while transformative, faces challenges in specificity, precision, delivery, accessibility, flexibility, and safety. This review addresses these limitations by highlighting strategies to reduce off‐target effects, exploring HDR‐based and alternative editing approaches, and evaluating advanced delivery mechanisms.
Muna Alariqi+8 more
wiley +1 more source
Mitochondrial Maintenance in Skeletal Muscle. [PDF]
de Smalen LM, Handschin C.
europepmc +1 more source
The action of adrenaline on mammalian skeletal muscle
G. L. Brown+2 more
openalex +2 more sources
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang+9 more
wiley +1 more source
Effect of Ether Anesthesia on Human Skeletal Muscle Metabolism [PDF]
DOROTHY H. HENNEMAN, LEHOY D. VANDAM
openalex +1 more source
Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun+15 more
wiley +1 more source
Selenium and Skeletal Muscle Health in Sports Nutrition. [PDF]
Wang Q, Huang J, Zhu K, Zuo W.
europepmc +1 more source