Gabpα‐Pparγ Complex Determines Glycolytic Capacity and Lactic Acid Homeostasis in Brown Fat
This study identifies the Gabpα–Pparγ complex as a key transcriptional regulator that couples glycolysis to lactate‐driven thermogenesis in brown adipose tissue by directly activating Eno1 transcription. Competitive disruption of this interaction impairs lactate metabolism and thermogenic capacity.
Zhihan Wang +22 more
wiley +1 more source
Correction to "In Vivo Optical Assessment of Cerebral and Skeletal Muscle Microvascular Response to Phenylephrine". [PDF]
europepmc +1 more source
Molecular Framework of the Onset and Progression of Skeletal Muscle Aging. [PDF]
Horlem T +3 more
europepmc +1 more source
Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao +8 more
wiley +1 more source
Influence of Neonatal Exposure to Hyperoxia on Skeletal Muscle in a Rat Model. [PDF]
Awata K +5 more
europepmc +1 more source
Dead Matter, Living Machines: Repurposing Crustaceans' Abdomen Exoskeleton for Bio‐Hybrid Robots
Crustacean exoskeletons, repurposed from food waste, are engineered into sustainable bending actuators combining biotic structure with synthetic control. The augmented exoskeletons achieve rapid and robust motion with lightweight body and can be used as part of robotic manipulators, grippers and swimmers.
Sareum Kim, Kieran Gilday, Josie Hughes
wiley +1 more source
CircHOMER1 in mediating porcine skeletal muscle development. [PDF]
Li M +8 more
europepmc +1 more source
Inspired by the composition and structure of native bone tissue and its complex interplay of biological signals, a norepinephrine‐loaded biomimetic mineralized electrocompacted collagen scaffold (NE‐MEC) is developed capable of simultaneously supporting osteogenesis, neural repair, angiogenesis, and immune modulation.
Zhengyun Ren +10 more
wiley +1 more source
The role of sestrin2 in skeletal muscle regeneration after injury. [PDF]
Hwang CY +8 more
europepmc +1 more source
Artificial Intelligence‐Driven Soft Bioelectronics for Self‐Powered Respiration Monitoring
Artificial intelligence‐driven soft bioelectronics for self powered respiration monitoring based on triboelectric nanogenerators (TENGs), piezoelectric nanogenerators (PENGs), and magnetoelastic generators (MEGs) enable continuous and multi‐scenario respiratory biomechanical data collection. Coupled with machine learning and big data driven diagnostics,
Xinkai Xu, Xiao Xiao, Rui Guo, Jun Chen
wiley +1 more source

