Results 261 to 270 of about 2,095,304 (391)

Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection

Advanced Science, EarlyView.
The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng, Yansong Wang, Haoyue Huang, Yinglong Ding, Jun Wang, Meili Liu, Kun Song, Lianbo Shao, You Yu, Ziying Yang, Zhenya Shen   +10 more
wiley   +1 more source

Quantitative measurement of morphometric indicators of skeletal muscle cell behaviour and quality. [PDF]

J R Soc Interface
Hardman D, Hennig K, Martins IB, Roman W, Gomes ER, Bernabeu MO.   +5 more
europepmc   +1 more source

Flexible Optoelectronic Hybrid Microfiber Long‐period Grating Multimodal Sensor

Advanced Science, EarlyView.
An entirely new optoelectronic hybrid multimodal optical fiber sensor which can simultaneously monitor biomechanics and glucose is demonstrated. The developed method simultaneously integrates two heterogeneous sensing mechanisms, optical and electrical, into a single sensor in a compact manner. Optical and electrical sensors can work simultaneously but
Zhenru Li, Li‐Peng Sun, Yanzhen Tan, Zhiwei Wang, Xiao Yang, Tiansheng Huang, Jie Li, Yi Zhang, Bai‐Ou Guan   +8 more
wiley   +1 more source

Unraveling the triad of immunotherapy, tumor microenvironment, and skeletal muscle biomechanics in oncology. [PDF]

Front Immunol
Ma S, Lu Y, Sui S, Yang JS, Fu BB, Tan PX, Chai Y, Lv J, Kong L, Wu X, Gao YB, Yan T.   +11 more
europepmc   +1 more source

Bacterial Capture‐Killing Capsules with Remodeling Bone Immune Microenvironment for the Effective Treatment of Osteomyelitis

Advanced Science, EarlyView.
The PC‐O@TOB capsules are designed to exhibit bactericidal effects, regulate the bone immune microenvironment by promoting M2 macrophage polarization, eliminate excessive ROS, and enhance bone regeneration, providing a novel multi‐dimensional approach for the treatment of osteomyelitis.
Dong Yang, Chang Shu, Chengwei Xu, Xingjie Zan, Shaoyin Wei, Chenglong Wang, Lianxin Li   +6 more
wiley   +1 more source

A semi-automated observation approach to quantify mouse skeletal muscle differentiation using immunohistochemistry. [PDF]

Physiol Rep
Shimizu K, Yoshida Y, Iwasa K, Fujii Y, Jacob UM, Fritsch T, Abdelhameed AS, Calabrese V, Osakabe N.   +8 more
europepmc   +1 more source

AuCu@CuO2 Aerogels with H2O2/O2 Self‐Supplying and Quadruple Enzyme‐Like Activity for MRSA‐Infected Diabetic Wound Management

Advanced Science, EarlyView.
The AuCu@CuO2 aerogels demonstrate favorable photothermal properties, four types of enzyme‐like activities, and H2O2/O2 self‐supplying to modulate the complex microenvironment of MRSA‐infected diabetic wounds. The results indicate that the AuCu@CuO2 aerogel can be activated by the microenvironment of diabetic wound infection, alleviating inflammation ...
Xiaofeng Tan, Nanyun Lin, Sha Yang, Hongyu Gong, Minghui Wang, Na Li, Fen Liu, Dajun Rao, Yingying Wu, Jing Tang, Qinglai Yang   +10 more
wiley   +1 more source

Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles

Advanced Science, EarlyView.
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang, Shiying Zhang, Irene Shuping Zhao, Xueqi Gan, Yang Zhang   +4 more
wiley   +1 more source

Neural stimulation suppresses mTORC1-mediated protein synthesis in skeletal muscle. [PDF]

Sci Adv
Dumitras AG, Piccoli G, Tellkamp F, Keufgens L, Baraldo M, Zorzato S, Cussonneau L, Nogara L, Krüger M, Blaauw B.   +9 more
europepmc   +1 more source

Effect of denervation and cocainization on the activity of creatine synthesing enzyme and phosphorylase in the skeletal muscle

, 1959
Takashi Matsui
openalex   +2 more sources