Results 71 to 80 of about 571,718 (317)

Muscle atrophy induced by SOD1^G93A expression does not involve the activation of caspase in the absence of denervation

Skeletal Muscle, 2011
Background The most remarkable feature of skeletal muscle is the capacity to adapt its morphological, biochemical and molecular properties in response to several factors. Nonetheless, under pathological conditions, skeletal muscle loses its adaptability,
Dobrowolny Gabriella, Aucello Michela, Musarò Antonio   +2 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Noninvasive Estimation of Myosin Heavy Chain Composition in Human Skeletal Muscle

, 2011
Purpose: Information on muscle fiber type composition is of great importance in muscle physiology and athletic performance. Because there are only a few techniques available that noninvasively and accurately provide an estimate of muscle fiber type ...
Rittweger, Jörn, JÖRN RITTWEGER, IGOR B. MEKJAVIĆ, Pisot, Rado, BOŠTJAN ŠIMUNIČ, Degens, Hans, Narici, M., Mekjavic, Igor, RADO PIŠOT, Pišot, R., MARCO NARICI, Degens, H., Simunic, Bostjan, Simunič, B., HANS DEGENS, Narici, Marco, Mekjavić, I. B., Rittweger, J.   +17 more
core   +1 more source

The role of mTOR complex 1 in skeletal muscle [PDF]

, 2012
An important factor in energy and nutrient pathways is the mammalian target of rapamycin complex 1 (mTORC1). The multiprotein complex, with the central component mTOR, regulates cell growth and survival.
Romanino, Klaas Emilio Antonius Anna
core   +1 more source

Linkages between changes in the 3D organization of the genome and transcription during myotube differentiation in vitro

Skeletal Muscle, 2017
Background The spatial organization of eukaryotic genomes facilitates and reflects the underlying nuclear processes that are occurring in the cell. As such, the spatial organization of a genome represents a window on the genome biology that enables ...
Malina D. Doynova, James F. Markworth, David Cameron-Smith, Mark H. Vickers, Justin M. O’Sullivan   +4 more
doaj   +1 more source

Expression of MuRF1 or MuRF2 is essential for the induction of skeletal muscle atrophy and dysfunction in a murine pulmonary hypertension model

Skeletal Muscle, 2020
Background Pulmonary hypertension leads to right ventricular heart failure and ultimately to cardiac cachexia. Cardiac cachexia induces skeletal muscles atrophy and contractile dysfunction.
Thanh Nguyen, T. Scott Bowen, Antje Augstein, Antje Schauer, Alexander Gasch, Axel Linke, Siegfried Labeit, Volker Adams   +7 more
doaj   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

The regulation of metabolic gene expression in human skeletal muscle by exercise: the influence of exercise intensity and contraction frequency [PDF]

, 2010
Skeletal muscle contraction increases energy expenditure and improves metabolic flexibility, but is also a key regulator of metabolic gene expression.
Carson, Brian
core  

Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. II -Genetic factors related to animal performance and advances in methodology [PDF]

, 2011
Selective breeding is an effective tool to improve livestock. Several selection experiments have been conducted to study direct selection responses as well as correlated responses in traits of skeletal muscle growth and function. Moreover, comparisons of
Wimmers, K, Nottingham, Te Pas, M. F. W., N. Oksbjerg, Te Pas, M. F.W., Stickland, N C, Algarve, Oksbjerg, Neils, Rehfeldt, C., Stickland, Neil, Rehfeldt, Charlotte, Brameld, J M, Picard, Brigitte, B., Te Pas, Marinus, Pas, M, Leibniz Inst Anim FBN, Nissen, P M, Power, D M, Valente, L M P, K. Wimmers, Oksbjerg, N, Nissen, Pia, Wimmers, Klaus, Valente, L.M.P., Brameld, J. M., M.F.W. Te Pas, Picard, B., Stickland, N.C., Pas, M.F.W., te, Berri, C., Picard, B, Nissen, P. M., B. Picard, Stickland, N. C., Berri, C, Rehfeldt, C, P.M. Nissen, Valente, L. M.P., Valente, Luísa, Power, Deborah, Wageningen UR, The Netherlands, Brameld, John, INRA, France, Nissen, P.M., te Pas, M.F.W., Brameld, J.M., Aarhus, C. Rehfeldt, Wimmers, K., N.C. Stickland, Power, D. M., C. Berri, D.M. Power, Valente, L. M. P., J.M. Brameld, Power, D.M., L.M.P. Valente, Berri, Cécile, Porto, Oksbjerg, N.   +59 more
core   +1 more source