Results 41 to 50 of about 604,468 (284)

A Self-Setting Hydrogel of Silylated Chitosan and Cellulose for the Repair of Osteochondral Defects: From in vitro Characterization to Preclinical Evaluation in Dogs

Frontiers in Bioengineering and Biotechnology, 2020
Articular cartilage (AC) may be affected by many injuries including traumatic lesions that predispose to osteoarthritis. Currently there is no efficient cure for cartilage lesions. In that respect, new strategies for regenerating AC are contemplated with
Cécile Boyer, Cécile Boyer, Gildas Réthoré, Gildas Réthoré, Gildas Réthoré, Pierre Weiss, Pierre Weiss, Pierre Weiss, Cyril d’Arros, Cyril d’Arros, Julie Lesoeur, Julie Lesoeur, Julie Lesoeur, Claire Vinatier, Claire Vinatier, Claire Vinatier, Boris Halgand, Boris Halgand, Boris Halgand, Olivier Geffroy, Olivier Geffroy, Olivier Geffroy, Marion Fusellier, Marion Fusellier, Marion Fusellier, Gildas Vaillant, Gildas Vaillant, Patrice Roy, Patrice Roy, Patrice Roy, Olivier Gauthier, Olivier Gauthier, Olivier Gauthier, Jérôme Guicheux, Jérôme Guicheux, Jérôme Guicheux, Jérôme Guicheux   +36 more
doaj   +1 more source

Exposure to environmental contaminants and folic acid supplementation intergenerationally impact fetal skeleton development through the paternal lineage in a rat model

Frontiers in Toxicology, 2022
Persistent organic pollutants (POPs) are ubiquitous in the environment, which is of concern since they are broadly toxic for wildlife and human health.
Phanie L. Charest, Phanie L. Charest, Emmanuel Tessougue, Emmanuel Tessougue, Maryse Lessard, Maryse Lessard, Pauline M. Herst, Pauline M. Herst, Pauline Navarro, Sarah Kimmins, Sarah Kimmins, Jacquetta M. Trasler, Amanda J. MacFarlane, Marie-Odile Benoit-Biancamano, Marie-Odile Benoit-Biancamano, Janice L. Bailey, Janice L. Bailey, Mathieu Dalvai, Mathieu Dalvai   +18 more
doaj   +1 more source

Skeleton based action recognition using translation-scale invariant image mapping and multi-scale deep cnn

, 2017
This paper presents an image classification based approach for skeleton-based video action recognition problem. Firstly, A dataset independent translation-scale invariant image mapping method is proposed, which transformes the skeleton videos to colour ...
Chen, Yucheng, Cheng, Xuelian, Dai, Yuchao, He, Mingyi, Li, Bo   +4 more
core   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Multiparametric influence of 3D-printed organo-mineral scaffolds on bone regeneration

Scientific Reports
The development of synthetic bone substitutes that equal or exceed the efficacy of autologous graft remains challenging. In this study, a rat calvarial defect model was used as a reference to investigate the influence of composition and architecture of ...
Touya Nicolas, Reiss Ségolène, Rouillon Thierry, Dutilleul Maeva, Veziers Joelle, Pare Arnaud, Brasset Ludmila, Weiss Pierre, Corre Pierre, Charbonnier Baptiste   +9 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Effects of Myostatin b Knockout on Offspring Body Length and Skeleton in Yellow Catfish (Pelteobagrus fulvidraco)

Biology, 2023
Based on obtaining mstnb gene knockout in Pelteobagrus fulvidraco, a study on the effect of the mstn gene on skeletal morphology and growth was performed by comparing the number and length of the vertebrae of mutant and wild-type fish in a sibling group ...
Xincheng Zhang, Fang Wang, Mi Ou, Haiyang Liu, Qing Luo, Shuzhan Fei, Jian Zhao, Kunci Chen, Qingshun Zhao, Kaibin Li   +9 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Structural Component Phenotypic Traits from Individual Maize Skeletonization by UAS-Based Structure-from-Motion Photogrammetry

Drones, 2023
The bottleneck in plant breeding programs is to have cost-effective high-throughput phenotyping methodologies to efficiently describe the new lines and hybrids developed.
Monica Herrero-Huerta, Diego Gonzalez-Aguilera, Yang Yang   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source