Results 41 to 50 of about 301,328 (249)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

CT scan-based morphometric comparison of human and canine lumbar spine generates instrumental data for intervertebral disc percutaneous surgery

open access: yesOsteoarthritis and Cartilage Open
Objective: This study aimed to describe the anatomical landmarks for intervertebral disc (IVD) percutaneous approaches (transpedicular TPA and transannular TAA) using CT scans in humans and dogs for regenerative medicine research.
N. Gavira   +12 more
doaj   +1 more source

Phosphate-dependent FGF23 secretion is modulated by PiT2/Slc20a2

open access: yesMolecular Metabolism, 2018
Objective: The canonical role of the bone-derived fibroblast growth factor 23 (Fgf23) is to regulate the serum inorganic phosphate (Pi) level. As part of a feedback loop, serum Pi levels control Fgf23 secretion through undefined mechanisms.
Nina Bon   +5 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Skeleton weed in Western Australia, pocket guide

open access: yes, 2009
The Skeleton Weed Program is a coordinated approach to eradicating skeleton weed in Western Australia. It is run jointly by the State Skeleton Weed Committee, the Department of Agriculture and the Agriculture Protection Board.
Agriculture Protection Board   +2 more
core   +2 more sources

Infrared and 3D Skeleton Feature Fusion for RGB-D Action Recognition

open access: yesIEEE Access, 2020
For skeleton-based action recognition from depth cameras, distinguishing object-related actions with similar motions is a difficult task. The other available video streams (RGB, infrared, depth) may provide additional clues, given an appropriate feature ...
Alban Main De Boissiere, Rita Noumeir
doaj   +1 more source

Curve Skeleton Extraction From 3D Point Clouds Through Hybrid Feature Point Shifting and Clustering

open access: yes, 2020
Curve skeleton is an important shape descriptor with many potential applications in computer graphics, visualization and machine intelligence. We present a curve skeleton expression based on the set of the cross‐section centroids from a point cloud model
Jin, Xiaogang   +5 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Historic Horse Family Displaying Malformations of the Cervicothoracic Junction and Their Connection to Modern German Warmblood Horses

open access: yesAnimals, 2023
Malformations of the equine cervicothoracic junction affect the C6 and C7 cervical vertebrae, the T1 thoracic vertebra and in variable extent the first and second sternal ribs. To date, the clinical impact of this malformation, its prevalence and mode of
Elisa Zimmermann   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

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