Results 51 to 60 of about 604,468 (284)
Scientific ReportsPeriodontitis is a prevalent chronic inflammatory disease due to the host response to dysbiotic biofilm. Immunohistochemistry is often used for a better and more functional tissue characterization.
Emilie Hascoët +6 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2020 Senescence is a cellular defense mechanism that helps cells prevent acquired damage, but chronic senescence, as in aging, can contribute to the development of age-related tissue dysfunction and disease.
Anuj K. Sharma +7 more
doaj +1 more source
Spacetime algebraic skeleton [PDF]
, 2002 The cosmological constant Lambda, which has seemingly dominated the primaeval Universe evolution and to which recent data attribute a significant present-time value, is shown to have an algebraic content: it is essentially an eigenvalue of a Casimir ...
Aldrovandi, R., Barbosa, A. L.
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Phosphate-dependent FGF23 secretion is modulated by PiT2/Slc20a2
Molecular Metabolism, 2018 Objective: The canonical role of the bone-derived fibroblast growth factor 23 (Fgf23) is to regulate the serum inorganic phosphate (Pi) level. As part of a feedback loop, serum Pi levels control Fgf23 secretion through undefined mechanisms.
Nina Bon +5 more
doaj +1 more source
Skeleton as a probe of the cosmic web: the 2D case
, 2003 We discuss the skeleton as a probe of the filamentary structures of a 2D random field. It can be defined for a smooth field as the ensemble of pairs of field lines departing from saddle points, initially aligned with the major axis of local curvature and
Colombi, D. Novikov, O. Dore, S. Colombi
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Intelligibility of Post-War Reconstruction in French Bombed Cities
Urban Planning, 2023 In the aftermath of the WWII, many French cities faced a great need for reconstruction in response to the heavy destruction caused by the bombardments.
Alice Vialard
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Osteoarthritis and Cartilage OpenObjective: This study aimed to describe the anatomical landmarks for intervertebral disc (IVD) percutaneous approaches (transpedicular TPA and transannular TAA) using CT scans in humans and dogs for regenerative medicine research.
N. Gavira +12 more
doaj +1 more source