Results 61 to 70 of about 42,356 (316)

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

The Synergy of Artificial Intelligence and 3D Bioprinting: Unlocking New Frontiers in Precision and Tissue Fabrication

Advanced Functional Materials, EarlyView.
Advances in integrating artificial intelligence into 3D bioprinting are systematically reviewed here. Machine learning, computer vision, robotics, natural language processing, and expert systems are examined for their roles in optimizing bioprinting parameters, real‐time monitoring, quality control, and predictive maintenance.
Joao Vitor Silva Robazzi, Irem Deniz Derman, Deepak Gupta, Logan Haugh, Yogendra Pratap Singh, Vaibhav Pal, Yasar Ozer Yilmaz, Suihong Liu, Andre Luis Dias, Rogerio Andrade Flauzino, Ibrahim Tarik Ozbolat   +10 more
wiley   +1 more source

Additively Manufactured 3D Auxetic Metamaterials for Structurally Guided Capacitive and Resistive Tactile Sensing

Advanced Functional Materials, EarlyView.
A 3D‐architected auxetic metamaterial is used to construct capacitive and resistive tactile sensors via digital light processing‐based additive manufacturing. The inward deformation of the proposed structure under compression amplifies local strain, enhancing sensing performance.
Mingyu Kang, Hong‐Gap Choi, Keun Park, Soonjae Pyo   +3 more
wiley   +1 more source

In Pursuit of True Wisdom: How the Re-Emergence of Classical Wonder Should Replace Descartes’s Neo-Averrostic Sophistry

Studia Gilsoniana, 2020
Modern mathematical physics often claims to make philosophy obsolete. This presentation aims to show that the modern concept of wisdom fundamentally diverges with the thinking of Descartes, that, strictly speaking, at least in his metaphysical first ...
Jason Nehez
doaj   +1 more source

From Exciton Dynamics to Cell Fate: A Carbon Dot Based NIR Photocatalytic Platform for Pyroptosis via Self‐Trapped Excitons

Advanced Functional Materials, EarlyView.
A facile and effective method to boost NIR light induced photocatalysis based on nontoxic NIR emissive carbon dots (nir‐CDs) via Self‐trapped excitons, showing that both O2− • and •OH can be generated from nir‐CDs under NIR laser irradiation. Abstract Near‐infrared (NIR) light‐triggered photocatalytic therapy remains a critical challenge in efficient ...
Qingcheng Wang, Quansheng Cheng, Bingzhe Wang, Tesen Zhang, Yupeng Liu, Ruifeng Zheng, Shi Chen, Guichuan Xing, Songnan Qu   +8 more
wiley   +1 more source

Beyond Scientism and Skepticism: An Integrative Approach to Global Mental Health

Frontiers in Psychiatry, 2015
The global burden of disorders has shifted from infectious disease to non-communicable diseases, including neuropsychiatric disorders. Whereas infectious disease can sometimes be combated by targeting single causal mechanisms, such as prevention of ...
Dan J Stein, Judy eIlles
doaj   +1 more source

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

Advanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore, Cristiano Pesce, Antonietta Greco, Claudia Pisante, Greta Avancini, Valentina Di Francesco, Yosi Shamay, Paolo Decuzzi   +7 more
wiley   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

Marriage and Its Representations in Classical Hollywood Comedy (19341945) : Stanley Cavell, the Concept of Skepticism and Kierkegaards Legacy

Journal for Religion, Film and Media, 2018
This article explores the questions of marriage and divorce as discussed by Stanley Cavell in his study of classical Hollywood comedies, in which he considered a popular subgenre of the American comedy of the thirties and forties that he dubbed the ...
El-Khoury, Toufic Ishaia
doaj   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source