Results 111 to 120 of about 1,364 (146)
Comparative Study of Cutaneous Squamous Cell Carcinogenesis in Different Hairless Murine Models. [PDF]
Cancers (Basel)Gkikas G +12 more
europepmc +1 more source
Radiation dermatitis in the hairless mouse model mimics human radiation dermatitis. [PDF]
Sci RepLawrence J +10 more
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Low molecular polypeptide from oyster hydrolysate recovers photoaging in SKH-1 hairless mice
Toxicology and Applied Pharmacology, 2020When the human skin is chronically exposed to external stimuli such as ultraviolet (UV) radiation, the skin tissue suffers damage and the structure of the extracellular matrix (ECM) in the skin is disrupted. This eventually causes symptoms such as wrinkles loss of elasticity, skin sagging, and skin cancer. We previously found that hydrolysate extracted
Joon Sok Bang, Se Young Choung
exaly +3 more sources
Enzyme-treated caviar extract ameliorates melanogenesis in UVB-induced SKH-1 hairless mice
Biochemical and Biophysical Research Communications, 2023This study investigated anti-melanogenesis effects of enzyme-treated caviar extract (CV) in murine melanoma B16F10 cells and SKH-1 hairless mice. To induce melanin production in vitro and in vivo studies, B16F10 cells were treated with 3-Isobutyl-1-methylxanthine (IBMX), and SKH-1 hairless mice were irradiated with UVB, respectively.
Yeankyoung Koo, Sukjin Kim
exaly +3 more sources
SKH-1 hairless mice repair UV-induced pyrimidine dimers in epidermal DNA
Journal of Photochemistry and Photobiology B: Biology, 1990The SKH-1 hairless mouse strain has been used extensively as a model for human photocarcinogenesis, photoimmunology and photoaging, but little is known about DNA repair in living mouse skin. Mice were irradiated with UV-B light at doses which produce mild to severe sunburn, and the frequency of pyrimidine dimers in epidermal DNA was measured ...
Daniel B Yarosh
exaly +3 more sources
Toxicology and Applied Pharmacology, 2004
Sulindac is a nonsteroidal anti-inflammatory drug with demonstrated potency as a chemopreventive agent in animal models of carcinogenesis and in patients with familial adenomatous polyposis. Because tumor promotion is generally associated with exposure to pro-inflammatory stimuli, it is likely that anti-inflammatory agents may have potent antitumor ...
Mohammad Athar +2 more
exaly +3 more sources
Sulindac is a nonsteroidal anti-inflammatory drug with demonstrated potency as a chemopreventive agent in animal models of carcinogenesis and in patients with familial adenomatous polyposis. Because tumor promotion is generally associated with exposure to pro-inflammatory stimuli, it is likely that anti-inflammatory agents may have potent antitumor ...
Mohammad Athar +2 more
exaly +3 more sources
Toxicology Letters, 2015
Sulfur mustard (SM) is a strong bifunctional alkylating agent that produces severe tissue injuries characterized by erythema, edema, subepidermal blisters and a delayed inflammatory response after cutaneous exposure. However, despite its long history, SM remains a threat because of the lack of effective medical countermeasures as the molecular ...
Thierry Douki, André Peinnequin
exaly +4 more sources
Sulfur mustard (SM) is a strong bifunctional alkylating agent that produces severe tissue injuries characterized by erythema, edema, subepidermal blisters and a delayed inflammatory response after cutaneous exposure. However, despite its long history, SM remains a threat because of the lack of effective medical countermeasures as the molecular ...
Thierry Douki, André Peinnequin
exaly +4 more sources
Cancer Research, 2007
Abstract Sunscreens partially filter UVB and, therefore, could partially prevent skin cancer; however, efficient approaches are desired to effectively prevent photocarcinogenesis. It is hypothesized that nontoxic pharmacologically active natural compounds can increase photoprotective effects. Our completed studies suggest that silibinin,
Mallikarjuna, Gu +4 more
openaire +2 more sources
Abstract Sunscreens partially filter UVB and, therefore, could partially prevent skin cancer; however, efficient approaches are desired to effectively prevent photocarcinogenesis. It is hypothesized that nontoxic pharmacologically active natural compounds can increase photoprotective effects. Our completed studies suggest that silibinin,
Mallikarjuna, Gu +4 more
openaire +2 more sources
Photo‐co‐carcinogenesis of Topically Applied Retinyl Palmitate in SKH‐1 Hairless Mice
Photochemistry and Photobiology, 2017AbstractCosmetic products that contain retinyl palmitate are popular as antiaging skin treatments; however, recent studies suggest a risk for enhanced skin tumor development with topical retinyl palmitate applications and exposure to solar ultraviolet radiation (UVR).
Mary D, Boudreau +7 more
openaire +2 more sources