Equity in Action: Disrupting Systemic Barriers to Specialty Skill Utilisation Among Internationally Qualified Nurses in Australia. [PDF]
Kurup C +3 more
europepmc +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
ArchesWeatherGen: Skillful and compute-efficient probabilistic weather forecasting with machine learning. [PDF]
Couairon G +4 more
europepmc +1 more source
The Need To Train Professional Ethics Skills in Students in Physical Education and Sports
The approach to ethics in the field of physical education and sports is related to education and school, being very important at every national and transnational level. The different decision-makers in the differently organized countries of the European
Natalia PUTIN
doaj
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Procedural Skills Decay in Emergency Medicine: A Scoping Review. [PDF]
Oskar K +5 more
europepmc +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
ENSO phase transition enables prediction of winter North Atlantic Oscillation one year ahead. [PDF]
Kim K, Lee MI, Scaife AA, Smith DM.
europepmc +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Assessing the influence of diverse skills on employability outcomes for IT undergraduates. [PDF]
Senadheera D, Wisenthige K.
europepmc +1 more source

