Results 241 to 250 of about 2,495,985 (308)

Unlocking collective resilience: the mediating role of team behaviors in the relationship between the structure and performance of sports startups. [PDF]

Front Psychol
Wang YT, Liu ZN, Lin GL, Du J.
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Daytime sleep following observational practice does not enhance a visual-spatial and a motor representation. [PDF]

Exp Brain Res
Panzer S, Hofstetter N, Schreiber M, Wright DL.   +3 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Is Social Media Use a Blessing or Cure for Motor Function and Skill Acquisition? An Opinion Paper. [PDF]

eNeuro
Fricke L, Wendeborn T, Ragert P.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Deliberate practice: The cornerstone of microsurgical therapy. [PDF]

Clin Adv Periodontics
Velásquez-Plata D, Burkhardt R.
europepmc   +1 more source

Balance Training: Toward a Comprehensive Understanding and Application of the Overload Principle in Motor Skill Acquisition. [PDF]

Eur J Sport Sci
Aune TK, Aune MA, Estensen V, Lorås H.
europepmc   +1 more source

The effect of digital video feedback on roundoff learning outcomes in gymnastics learning. [PDF]

Front Sports Act Living
Fauzi RA, Suherman A, Saptani E, Tingsabhat S, Heryanto M.   +4 more
europepmc   +1 more source