Results 131 to 140 of about 626,223 (266)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Can Hobbies Shape Fine Motor Skills Development in First-Year Dental and Oral Health Students? [PDF]

Eur J Dent Educ
Shetty S, Tran C, Sexton C.
europepmc   +1 more source

Perceptions of the motivational climate, basic psychological needs, and life skills development in Chinese physical education students. [PDF]

Front Psychol, 2023
Zheng S, Ji X, Cheng L, Xu J, Cronin LD.
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Impact of the Practice of Playing Video Games on Technical Skills Development in Preclinical Dental Education: Preliminary Cross-Sectional Observational Study. [PDF]

JMIR Form Res
Clouet R, Remaud T, Boeffard C, Serisier S, Gaudin A, Prud'homme T.   +5 more
europepmc   +1 more source

RQ Labs: A Cybersecurity Workforce Skills Development Framework. [PDF]

Inf Syst Front, 2023
Daniel C, Mullarkey M, Agrawal M.
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Intergenerational effects of parental positive childhood experiences on social skills development in Chinese preschoolers: the moderating role of the home-rearing environment. [PDF]

Front Psychol
Yuan X, Zhu Z, Wang Y, Zhao R, Sun Y, Li X, Gao H, Anme T.   +7 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Melodic bridges: music intervention as a catalyst for social skills development in preschool children with autism. [PDF]

Front Psychol
Yang J, Zhang R.
europepmc   +1 more source