Results 151 to 160 of about 21,053,299 (356)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Knowledge-based Economic Development as a Unifying Vision in a Post-awakening Arab World [PDF]

This article traces the evolution of knowledge-based economic development in the Arab World. In pursuing this objective, many countries in the region have made large state-driven human capital investments with the goals of job creation, economic ...
Schwalje, Wes
core   +1 more source

Teaching flexible manufacturing system in university education for future engineers [PDF]

, 2007
Flexible Manufacturing System (FMS) typically possesses multiple automated stations and is capable of variable routing among stations. Human resource development, equipment operator skills, manufacture of processing tools, products, processes ...
Hilmi, Ahmad Humaizi, Rajamony, Bhuvenesh   +1 more
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Effect of Employer Branding on Talent Attraction in Ghana: Exploring the Roles of Employer Trust and Social Media Engagement

Journal of Human Resource Management
Purpose – This study assesses the effect of employer branding on talent attraction, exploring the Roles of employer trust and social media engagement.
Evans OWUSU ACHEAMPONG, Esther GLOVER, Richmond ADU-POKU, Evans OSEI BEMPAH, Christian OPOKU BOAHEN   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Success Factors of the Consultant Selection Stage of the Ghanaian Public Construction Projects: The Road Sector’s Perspective

Construction Economics and Building
The success of the Ghanaian public road construction phase and other preconstruction phases have been studied. However, the success of the Ghanaian public road project consultant selection phase has not received any attention, even though it is prone to
Chelteau Barajei, Elijah Kusi, Frank Ackon, Abdul Manaan Osman, Abdul Muhsin Zambang Mohammed, Frederick Simpeh, Francis Gyimah   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

History of mathematics as context for improving strategy flexibility in cubic equations

Frontiers in Education
Studies show that using original historical sources as a context for teaching problem-solving enhance students problem-solving skills and mathematical understanding.
Alfred Gyasi Bannor, Joseph Frank Gordon, Yarhands Dissou Arthur   +2 more
doaj   +1 more source