Results 41 to 50 of about 2,559 (287)

Vortex-Resistance Hypothesis: Large Eddy Simulation of Turbulent Flow in Isolated Pool- Riffle Units

E3S Web of Conferences, 2018
By numerical simulations of turbulent flow in isolated poolriffle units with various riffle heights, four different types of vortices were found and named as follows: surface rollers (SR), corner rollers (CR), ramp rollers (CR), and axial tails (AT ...
Dashtpeyma Hamed, MacVicar Bruce
doaj   +1 more source

Energy Loss in Skimming Flow over Cascade Spillways: Comparison of Artificial Intelligence-Based and Regression Methods

Applied Sciences, 2020
In this study, the energy dissipation of cascade spillways was studied by conducting a series of laboratory experiments. Five spillways slope angles (α) (10°, 20°, 30°, 40°, and 50°), various step numbers (N) ranging from 4 to 75, and a wide range of ...
Meysam Nouri, Parveen Sihag, Farzin Salmasi, Ozgur Kisi   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Experimental Study on Sediment Control in a Lateral Intake Channel by Using a Spur Dike Combined with a Skimming Wall [PDF]

Advances in Civil Engineering and Environmental Science
Water diversion using lateral intakes often leads to the issue of sediment entering water transmission systems. Failure to control sediment at the intake results in its transfer into irrigation canals and facilities, causing numerous problems in various ...
Amir Moradinejad, Amir Hamzeh Haghiabi, Mojtaba Saneie, Hojjatallah Younesi   +3 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Interactions between cavity flow and main stream skimming flows: an experimental study [PDF]

Canadian Journal of Civil Engineering, 2004
In the last two decades, research on the hydraulics of skimming flows down stepped chutes was driven by needs for better design guidelines. Skimming flows are characterized by significant momentum transfer from the main stream to the recirculation zones.
Gonzalez, Carlos A., Chanson, Hubert
openaire   +3 more sources

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Re-aeration in skimming flow over stepped chutes: two-dimensional CFD modeling and empirical equations [PDF]

RBRH
Flows in stepped chutes and spillways are highly turbulent and have the potential of absorbing and desorbing volatile compounds. The present work aimed to model the interfacial mass transfer in skimming flows using the two-resistance model and the ...
Thiago Reis Pereira Minho, André Luiz Andrade Simões, Luciano Matos Queiroz, Gemima Santos Arcanjo, Harry Edmar Schulz, Rodrigo de Melo Porto, Julio Cesar de Souza Inácio Gonçalves   +6 more
doaj   +1 more source

A smoothly curved body skimming on shallow water [PDF]

, 2021
We investigate the dynamics of a smoothly curved convex body skimming on a layer of shallow water, with the phenomenon of skipping stones as a primary modelling motivation but also industrial applications in mind.
Liu, K, Smith, F
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