Results 61 to 70 of about 775 (254)
Caractéristiques diphasiques des écoulements sur les coursiers en marches d'escalier [PDF]
, 2001 Stepped cascades and spillways have been used for more than 3,500 years. The recent regain of interest for the stepped chute design is associated with the introduction of new construction techniques, the development of new design techniques and newer ...
Chanson, H., Hubert Chanson
core +1 more source
Advanced Science, EarlyView.FAK signaling drives chemoresistance and tumor evolution in pancreatic ductal adenocarcinoma. The FAK inhibitor IN10018 restores gemcitabine sensitivity by inducing SLC7A11‐mediated ferroptosis through the PI3K‐Akt pathway and remodeling the tumor microenvironment, reducing mesenchymal components while enhancing CD8+ T‐cell infiltration in preclinical ...
Yingjin Wang +11 more
wiley +1 more source
Advanced Science, EarlyView.This study integrates two complementary traditional Chinese medicine components as precursors to synthesize bioactive AM‐AS@CDs. Compared with single‐component CDs, these dual‐component CDs exhibit enhanced antioxidant capacity and superior renoprotective effects.
Bixiao Liu +10 more
wiley +1 more source
Microsphere skimming in the porcine coronary arteries: Implications for flow quantification
Microvascular Research, 2015 Particle skimming is a phenomenon where particles suspended in fluid flowing through vessels distribute disproportionately to bulk fluid volume at junctions. Microspheres are considered a gold standard of intra-organ perfusion measurements and are used widely in studies of flow distribution and quantification.
Sinclair, Matthew +9 more
openaire +6 more sources
Numerical and Physical Modelling of Aerated Skimming Flows over Stepped Spillways [PDF]
, 2019 Stepped spillways are commonly used to control overflows from reservoirs, as they dissipate significantly more energy than smooth spillways. At high discharges, skimming flow occurs over stepped spillways, in which significant air entrainment occurs ...
van Alwon, Jacob Christian
core
Advanced Science, EarlyView.IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng +7 more
wiley +1 more source
Advanced Science, EarlyView.MERTK is upregulated in fibrotic macrophages and regulates the expression and activity of SRC and TKS5 through SPP1, mediating transdifferentiation of macrophages‐to‐myofibroblasts (MMT) and promoting pulmonary fibrosis. The figure was created with BioRender.com.
Yungeng Wei +3 more
wiley +1 more source
Advanced Science, EarlyView.A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng +5 more
wiley +1 more source
Shallow-water skimming, skipping and rebound problems [PDF]
, 2017 The subject of water-entry related problems has a wide range of applications in industries and natural sciences. In this thesis we study the dynamics of a solid body slamming, skimming, rebounding or sinking in shallow water. We reconcile and extend some
Liu, J
core
Jet Flow on Stepped Spillways [PDF]
, 1995 The authors provided interesting data on stepped spillway flows. The writer would like to add some information on flow resistance of skimming flows and discuss the energy dissipation on stepped chutes.
Chanson, Hubert
core +1 more source