Results 91 to 100 of about 6,156,020 (403)

The Role of Podoplanin in Skin Diseases [PDF]

, 2022
Jun Asai
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Consensus Recommendations for Treatment Strategies in Indians Using Botulinum Toxin and Hyaluronic Acid Fillers

Plastic and Reconstructive Surgery, Global Open, 2017
Background:. Indians constitute one of the largest population groups in the world. Facial anthropometry, morphology, and age-related changes in Indians differ from those of other ethnic groups, necessitating a good understanding of their facial structure
Krishan Mohan Kapoor, MCh, DNB, Vandana Chatrath, MD, MSc, Chytra Anand, DD, MSc, Rashmi Shetty, MD, Chiranjiv Chhabra, MD, Kuldeep Singh, MCh, Maya Vedamurthy, MD, Jamuna Pai, MBBS, Bindu Sthalekar, MD, Rekha Sheth, MD, on behalf of the Indian Facial Aesthetics Expert Group   +10 more
doaj   +1 more source

European sea bass (Dicentrarchus labrax) skin and scale transcriptomes [PDF]

, 2017
Fish skin and their appendages, the mineralized scales, are important organs for protection and homeostasis, but little is known about their specific transcript or protein repertoire.
Pinto, Patricia IS, Power, Deborah, Thorne, Michael A. S.   +2 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Histopathological Features of Nevus Sebaceous and Superimposed Skin Tumors

Journal of Skin Cancer
Conclusion: Our study revealed that malignant tumors were more common than benign lesions in patients with NS. Benign neoplasms were more frequent in women. Malignant neoplasms were detected in patients aged more than 25 years.
Paridokht Karimian, Naz Zargar Javaheri, Kaveh Gharaei Nejad, Hojat Eftekhari, Elahe Rafiei, Rana Rafiei   +5 more
doaj   +1 more source

Tricyclazole alleviates Fonsecaea pedrosoi-induced immune suppression of neutrophils by inhibiting DHN-melanin biosynthesis

Frontiers in Cellular and Infection Microbiology
IntroductionChromoblastomycosis (CBM) is a chronic cutaneous infection caused by dematiaceous fungi, characterized by therapeutic challenges such as difficulty in pathogen clearance and high recurrence rates. Fonsecaea pedrosoi (F.
Chunjiao Zheng, Wei Li, Yuanyuan Wang, Lulu Li, Linan Ni, Xiaoping Liu, Jingwen Tan, Lianjuan Yang, Qian Yu   +8 more
doaj   +1 more source

Pathological Skin Picking: Case Presentation and Review of the Literature [PDF]

, 2015
Pathological skin picking is a condition in which patients induce skin lesions through repetitive, compulsive excoriations of normal skin or skin with minor surface irregularities and they admit their role in the production of the lesions, but are unable
Benea, Vasile, Georgescu, Simona Roxana, Leahu, Diana, Raileanu, Cristina, Sarbu, Maria Isabela, Tampa, Mircea   +5 more
core   +3 more sources

Adhesive Hemostatic Conducting Injectable Composite Hydrogels with Sustained Drug Release and Photothermal Antibacterial Activity to Promote Full-Thickness Skin Regeneration During Wound Healing.

Small, 2019
Developing injectable nanocomposite conductive hydrogel dressings with multifunctions including adhesiveness, antibacterial, and radical scavenging ability and good mechanical property to enhance full-thickness skin wound regeneration is highly desirable
Yongping Liang, Xin Zhao, Tianli Hu, Baojun Chen, Z. Yin, P. Ma, Baolin Guo   +6 more
semanticscholar   +1 more source