Results 61 to 70 of about 4,250,920 (342)

Single-cell transcriptomics analysis of bullous pemphigoid unveils immune-stromal crosstalk in type 2 inflammatory disease

Nature Communications
Bullous pemphigoid (BP) is a type 2 inflammation- and immunity-driven skin disease, yet a comprehensive understanding of the immune landscape, particularly immune-stromal crosstalk in BP, remains elusive.
Tingting Liu, Zhenzhen Wang, Xiaotong Xue, Zhe Wang, Yuan Zhang, Zihao Mi, Qing Zhao, Lele Sun, Chuan Wang, Peidian Shi, Gongqi Yu, Meng Wang, Yonghu Sun, Fuzhong Xue, Hong Liu, Furen Zhang   +15 more
doaj   +1 more source

Necrotic Ulcers from Occlusive Vasculopathy Associated with Monoclonal B Cell Lymphocytosis

Acta Dermato-Venereologica, 2023
is missing (Shot communication) 
Delwyn Zhi Jie Lim, Shang-Ian Tee, Ling Cao, Ding Yuan Wang   +3 more
doaj   +1 more source

Curious Skin [PDF]

, 2010
Some of Henry Wellcome’s collection of tattoos on human skin will be on display in our forthcoming Skin exhibition. But how did the Parisian doctor from whom they were acquired come by his macabre collection of tattoos in the first place, and what did ...
Angel, G
core  

IC-integrated flexible shear-stress sensor skin [PDF]

, 2003
This paper reports the successful development of the first IC-integrated flexible MEMS shear-stress sensor skin. The sensor skin is 1 cm wide, 2 cm long, and 70 /spl mu/m thick. It contains 16 shear-stress sensors, which are arranged in a 1-D array, with
Ho, Chih-Ming, Huang, Adam, Tai, Yu-Chong, Xu, Yong   +3 more
core   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Development and evaluation of a rapid diagnostic method for Sporothrix globosa in Asia using quantitative real-time PCR

BMC Infectious Diseases
Background Sporotrichosis is a chronic granulomatous infection of the skin and subcutaneous tissue that can affect any organ through lymphatic spread. The prevalence of sporotrichosis infections is increasing and its treatment is challenging as there are
Hanqing Geng, Lele Sun, Chuan Wang, Yong Zhang, Shufen Wang, Yanru Cheng, Fangfang Bao, Hong Liu, Furen Zhang   +8 more
doaj   +1 more source

Skin blood flow changes during apneic spells in preterm infants [PDF]

, 1989
Changes in skin blood flow during apneic spells were determined in 18 preterm infants using a diode laser Doppler flow meter without light conducting fibres.
Aarnoudse, J.G., Greve, J., Jentink, H.W., Mul, F.F.M. de, Okken, A., Suichies, H.E.   +5 more
core   +2 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Evaluation of the efficacy and safety of ionic liquids containing ketoconazole in patients with tinea pedis: A randomized controlled clinical trial

Bioengineering & Translational Medicine, 2023
Ionic liquids (ILs) loading ketoconazole (KCZ) have shown better efficacy on rats with tinea pedis than the marketed Daktarin® but clinical studies are still lacking.
Xiying Wu, Min Shen, Huan Wang, Xue He, Jingwen Tan, Ruiping Wang, Lianjuan Yang, Hong Yang, Jianping Qi, Zhongjian Chen, Quangang Zhu   +10 more
doaj   +1 more source