Results 21 to 30 of about 187,636 (307)

Development and Evaluation of an In Silico Dermal Absorption Model Relevant for Children

Pharmaceutics, 2022
The higher skin surface area to body weight ratio in children and the prematurity of skin in neonates may lead to higher chemical exposure as compared to adults.
Yejin Esther Yun, Daniella Calderon-Nieva, Abdullah Hamadeh, Andrea N. Edginton   +3 more
doaj   +1 more source

Dermal Exposure Associated with Occupational End Use of Pesticides and the Role of Protective Measures

Safety and Health at Work, 2013
Background: Occupational end users of pesticides may experience bodily absorption of the pesticide products they use, risking possible health effects.
Ewan MacFarlane, Renee Carey, Tessa Keegel, Sonia El-Zaemay, Lin Fritschi   +4 more
doaj   +1 more source

High-Payload Nanosuspension of Centella asiatica Extract for Improved Skin Delivery with No Irritation

International Journal of Nanomedicine, 2021
Eun A Kim, Jun Soo Park, Min Seop Kim, Min Young Jeong, Hyun Jin Park, Jun Hyuk Choi, Jae Hee Seo, Yong Seok Choi, Myung Joo Kang College of Pharmacy, Dankook University, Cheonan, Chungnam, 330-714, KoreaCorrespondence: Myung Joo KangCollege of Pharmacy,
Kim EA, Park JS, Kim MS, Jeong MY, Park HJ, Choi JH, Seo JH, Choi YS, Kang MJ   +8 more
doaj  

ABSORPTION OF CARBOLIC ACID THROUGH THE SKIN. [PDF]

The Lancet, 1922
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openaire   +3 more sources

Improving Water Solubility and Skin Penetration of Ursolic Acid through a Nanofiber Process to Achieve Better In Vitro Anti-Breast Cancer Activity

Pharmaceutics
Woman’s breast cancer has always been among the top ten causes of cancer death, and nearly 2% to 5% of locally advanced breast cancers develop a fungating breast wound.
Hsuan Fu, Tzu-Hui Wu, Chih-Peng Ma, Feng-Lin Yen   +3 more
doaj   +1 more source

Shaving area of unwanted hair before laser operation is useful in cosmetic procedure: A simulation study

Journal of Dermatology and Dermatologic Surgery, 2015
In laser dermatology applications, the process of photon absorption, the reflectance and the thermal energy diffusion in the target tissue and its surrounding tissue during laser irradiation is crucial.
Farhad H. Mustafa, Mohamad S. Jaafar
doaj   +1 more source

Skin Barrier Function in Infants: Update and Outlook

Pharmaceutics, 2022
A good understanding of infant skin should provide a rationale for optimum management of the health of this integument. In this review, we discuss the skin barrier function of infants, particularly with reference to the use of diapers and baby wipes. The
Annisa Rahma, Majella E. Lane
doaj   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

In vitro and ex-vivo evaluation of topical formulations designed to minimize transdermal absorption of Vitamin K1. [PDF]

PLoS ONE, 2018
Topical application of Vitamin K1 has been demonstrated to effectively treat papulopustular skin rash, a serious and frequently encountered side effect of Epidermal Growth Factor Inhibitors (EGFRIs).
Ramina Nabiee, Barent Dubois, Laura Green, Ajay Sharma, Siu Fun Wong, Hamidreza Montazeri Aliabadi   +5 more
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source