Pharmacokinetic studies of drug absorption into human skin [PDF]
PhDOptimum therapeutic outcomes require not only proper drug selection but also effective drug delivery and monitoring. The aim of this thesis was to A) study drug delivery through the skin with a liquid formulated to promote absorption, B) develop ...
Al-Otaibi, Faisal Obaid
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Modeling the sampling volume for the skin blood oxygenation measurements [PDF]
The absolute quantified measurement of haemoglobin skin blood saturation from collected reflectance spectra of the skin is complicated by the fact that the blood content of tissues can vary both in the spatial distribution and in the amount.
Meglinski, I. V., Matcher, S. J.
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Analysis of skin tissues spatial fluorescence distribution by the Monte Carlo simulation [PDF]
A novel Monte Carlo technique of simulation of spatial fluorescence distribution within the human skin is presented. The computational model of skin takes into account the spatial distribution of fluorophores, which would arise due to the structure of
Churmakov, D. Y. +3 more
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Quantitative assessment of skin layers absorption and skin reflectance spectra simulation in the visible and near-infrared spectral regions [PDF]
We have simulated diffuse reflectance spectra of skin by assuming a wavelength-independent scattering coefficient for the different skin tissues and using the known wavelength dependence of the absorption coefficient of oxy- and deoxyhaemoglobin and ...
Meglinski, Igor V., Matcher, Stephen J.
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Modelling the effect of mixture components on permeation through skin [PDF]
A vehicle influences the concentration of penetrant within the membrane, affecting its diffusivity in the skin and rate of transport. Despite the huge amount of effort made for the understanding and modelling of the skin absorption of chemicals, a ...
E.G. Samaras +11 more
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Enhanced chlorhexidine skin penetration with eucalyptus oil [PDF]
Background Chlorhexidine digluconate (CHG) is a widely used skin antiseptic, however it poorly penetrates the skin, limiting its efficacy against microorganisms residing beneath the surface layers of skin. The aim of the current study was to improve the
Conway, Barbara R +26 more
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You are what you eat : Within-subject increases in fruit and vegetable consumption confer beneficial skin-color changes [PDF]
R Whitehead was funded by an ESRC Studentship.Background: Fruit and vegetable consumption and ingestion of carotenoids have been found to be associated with human skin-color (yellowness) in a recent cross-sectional study. This carotenoid-based coloration
Xiao, Dengke +15 more
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Penetration of Chlorhexidine into Human Skin [PDF]
This study evaluated a model of skin permeation to determine the depth of delivery of chlorhexidine into full-thickness excised human skin following topical application of 2% (wt/vol) aqueous chlorhexidine digluconate.
Karpanen, T. J. +11 more
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Computer simulation of the skin reflectance spectra [PDF]
The reflectance spectra of the human skin in visible and near-infrared (NIR) spectral region have been calculated using the Monte Carlo technique, and the specular and internal reflection on the medium surface is taken into account.
Meglinski, I. V., Matcher, S. J.
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Effect of beta-carotene supplementation on African skin [PDF]
The authors were funded by the South African National Research Foundation (V.C.), the British Academy, and Wolfson Foundation (D.P.).The quantification of skin carotenoid levels has a range of applications in Caucasian populations, from serving as a ...
Perrett, D.I. +4 more
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