The Phenion (R) Full-Thickness Skin Model for Percutaneous Absorption Testing [PDF]
In recent years many efforts have been made to replace dermal toxicity testing of chemicals in the animal by in vitro assays. As a member of a German research consortium, we have previously contributed to the validation of an in vitro test protocol for ...
Korting, Hans Christian +9 more
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Quantitative assessment of skin layers absorption and skin reflectance spectra simulation in the visible and near-infrared spectral regions [PDF]
We have simulated diffuse reflectance spectra of skin by assuming a wavelength-independent scattering coefficient for the different skin tissues and using the known wavelength dependence of the absorption coefficient of oxy- and deoxyhaemoglobin and ...
Meglinski, Igor V., Matcher, Stephen J.
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Analysis of skin tissues spatial fluorescence distribution by the Monte Carlo simulation [PDF]
A novel Monte Carlo technique of simulation of spatial fluorescence distribution within the human skin is presented. The computational model of skin takes into account the spatial distribution of fluorophores, which would arise due to the structure of
Churmakov, D. Y. +3 more
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Evaluation of Calcipotriol Solid Lipid Nanoparticles in Male BALB/c Mice Psoriasis Model [PDF]
Background and purpose: Psoriasis is an autoimmune inflammatory disease with major skin involvement. Calcipotriol as a vitamin-D analogue is one of the common drugs for topical treatment of psoriasis.
Mahsa Narenji +5 more
doaj
Modelling the effect of mixture components on permeation through skin [PDF]
A vehicle influences the concentration of penetrant within the membrane, affecting its diffusivity in the skin and rate of transport. Despite the huge amount of effort made for the understanding and modelling of the skin absorption of chemicals, a ...
E.G. Samaras +11 more
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Enhanced chlorhexidine skin penetration with eucalyptus oil [PDF]
Background Chlorhexidine digluconate (CHG) is a widely used skin antiseptic, however it poorly penetrates the skin, limiting its efficacy against microorganisms residing beneath the surface layers of skin. The aim of the current study was to improve the
Conway, Barbara R +26 more
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Penetration of Chlorhexidine into Human Skin [PDF]
This study evaluated a model of skin permeation to determine the depth of delivery of chlorhexidine into full-thickness excised human skin following topical application of 2% (wt/vol) aqueous chlorhexidine digluconate.
Karpanen, T. J. +11 more
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Computer simulation of the skin reflectance spectra [PDF]
The reflectance spectra of the human skin in visible and near-infrared (NIR) spectral region have been calculated using the Monte Carlo technique, and the specular and internal reflection on the medium surface is taken into account.
Meglinski, I. V., Matcher, S. J.
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Fruit, vegetable and dietary carotenoid intakes explain variation in skin-color in young caucasian women : a cross-sectional study [PDF]
This work was supported by a scholarship top-up grant from HMRI. Kristine Pezdirc is supported by an Australian Postgraduate Awards scholarship. Melinda Hutchesson is supported by a Postdoctoral Fellowship (100177) from the National Heart Foundation of ...
Hutchesson, Melinda J. +13 more
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You are what you eat : Within-subject increases in fruit and vegetable consumption confer beneficial skin-color changes [PDF]
R Whitehead was funded by an ESRC Studentship.Background: Fruit and vegetable consumption and ingestion of carotenoids have been found to be associated with human skin-color (yellowness) in a recent cross-sectional study. This carotenoid-based coloration
Xiao, Dengke +14 more
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