Results 31 to 40 of about 2,049,238 (291)

Analytical Method Development and Dermal Absorption of Pyrogallol, a Hair Dye Ingredient

open access: yesToxics, 2022
Pyrogallol is an ingredient in hair dye. Its concentration in hair dye is managed at less than 2.0% in Korea. There have been no reports on the dermal absorption rate of pyrogallol.
Yu-Jin Kim   +5 more
doaj   +1 more source

An In vivo Comparison of Biomimetic vs. Traditional Skin Moisturization [PDF]

open access: yes, 2015
The aim of this study was to determine whether a biomimetic cream can deliver superior moisturisation to the skin of human volunteers aged over 60, compared to the effects of a conventional moisturiser containing high levels of petrolatum and mineral oil.
Kurimo, Ritva   +3 more
core   +4 more sources

Rubus caesius leaves and stems in antiaging skin care products: antityrosinase, anticollagenase, antimicrobial activity, and transdermal distribution of main phenolic acids

open access: yesPharmaceutical Biology
Context The skin is the largest organ of the body, and its proper care significantly influences the well-being of the entire organism. Therefore, the ingredients of cosmetics and dermocosmetics should inhibit processes leading to inflammation and ...
Anna Hering   +8 more
doaj   +1 more source

Race, pigmentation, and the human skin barrier—considerations for dermal absorption studies

open access: yesFrontiers in Toxicology, 2023
A functional human skin barrier is critical in limiting harmful exposure to environmental agents and regulating the absorption of intentionally applied topical drug and cosmetic products.
Alec T. Salminen   +2 more
doaj   +1 more source

Morphine Metabolism in Human Skin Microsomes [PDF]

open access: yes, 2012
For patients with severe skin wounds, topically applied morphine is an option to induce efficient analgesia due to the presence of opioid receptors in the skin.
Heilmann, S.   +4 more
core   +1 more source

Nanotechnology in medicine and relevance to dermatology: Present concepts

open access: yesIndian Journal of Dermatology, 2012
Nanotechnology and nanomedicine are complementary disciplines aimed at the betterment of human life. Nanotechnology is an emerging branch of science for designing tools and devices of size 1-100 nm, with unique functions at the cellular, atomic and ...
K H Basavaraj
doaj   +1 more source

Development and Evaluation of an In Silico Dermal Absorption Model Relevant for Children

open access: yesPharmaceutics, 2022
The higher skin surface area to body weight ratio in children and the prematurity of skin in neonates may lead to higher chemical exposure as compared to adults.
Yejin Esther Yun   +3 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Improving Water Solubility and Skin Penetration of Ursolic Acid through a Nanofiber Process to Achieve Better In Vitro Anti-Breast Cancer Activity

open access: yesPharmaceutics
Woman’s breast cancer has always been among the top ten causes of cancer death, and nearly 2% to 5% of locally advanced breast cancers develop a fungating breast wound.
Hsuan Fu   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

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