Results 61 to 70 of about 187,636 (307)

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

Advanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu, Jueun Kim, Dae‐Hyun Kim, Sewoom Baek, Suji Park, Seyong Chung, Hak‐Joon Sung   +6 more
wiley   +1 more source

Harnessing Outer Space for Improved Electrocaloric Cooling

Advanced Functional Materials, EarlyView.
A novel radiative heat sink/source‐integrated electrocaloric (R‐iEC) system combines the electrocaloric (EC) effect with a thermally conductive radiative cooler (TCRC) to address heat dissipation limitations in EC devices. Utilizing outer space as a heat sink, the system achieves up to 240 W m−2 of heat dissipation performance, making it highly ...
Dong Hyun Seo, Hyung Rae Kim, Joo Ho Yun, Hyunkyu Kwak, Do Hyeon Kim, Se‐Yeon Heo, Rujun Ma, Gil Ju Lee, Young Min Song   +8 more
wiley   +1 more source

Percutaneous Absorption of Fireground Contaminants: Naphthalene, Phenanthrene, and Benzo[a]pyrene in Porcine Skin in an Artificial Sweat Vehicle

Toxics
Firefighters face significant risks of exposure to toxic chemicals, such as polycyclic aromatic hydrocarbons (PAHs), during fire suppression activities.
Chandler Probert, Emma Nixon, R. Bryan Ormond, Ronald Baynes   +3 more
doaj   +1 more source

Self‐Cascade Catalytic Reaction–Assisted Apoptosis/Calcicoptosis/Ferroptosis Induction with Microsphere‐Aggregated Hydrogels in Triple‐Negative Breast Cancer Therapy

Advanced Functional Materials, EarlyView.
Hyaluronic acid‐dopamine‐based intra‐crosslinked microsphere including cisplatin (HPC MS) is fabricated by spray‐drying and calcium/iron ions are introduced for interparticle crosslinking. Designed microsphere‐aggregated hydrogel (MAH) system including cisplatin/CaO2/FeSO4 can provide apoptosis/calcicoptosis/ferroptosis‐mediated chemo/cascade ...
ChaeRim Hwang, Yeoung Eun Choi, Song Yi Lee, Mrinmoy Karmakar, Qiaojun Hao, Junmin Lee, Hyun‐Jong Cho   +6 more
wiley   +1 more source

Engineered Peptides‐Based Hybrid‐Nested Microneedle Effectively Treat Biofilm‐Infected Diabetic Wounds

Advanced Functional Materials, EarlyView.
A hybrid‐nested microneedle/cryogel scaffold (MQW‐CMg‐MOF) is designed for efficient biofilm removal and accelerated healing of diabetic wounds. The scaffold shows substantial biofilm removal in vitro and in a preclinical diabetic swine biofilm‐infected wound model compared to the control.
Syed Muntazir Andrabi, S. M. Shatil Shahriar, Yiran Tian, Farzad Hayati, Yajuan Su, Feng Zhang, Navatha Shree Sharma, Guangshun Wang, Shannon L. Wong, Zheng Yan, Guoliang Huang, Jingwei Xie   +11 more
wiley   +1 more source

Stratum Corneum‐Inspired Zwitterionic Hydrogels with Intrinsic Water Retention and Anti‐Freezing Properties for Intelligent Flexible Sensors

Advanced Functional Materials, EarlyView.
A novel stratum corneum‐inspired zwitterionic hydrogel is developed for intelligent, flexible sensors, featuring intrinsic water retention and anti‐freezing properties. The quasi‐gel, composed of hygroscopic polymers and bound water, maintains its softness across a wide range of humidity.
Meng Wu, Chenyu Qiao, Peng‐Fei Sui, Jing‐Li Luo, Zuoli Li, Yi Cao, Renjun Pei, Xuwen Peng, Hongbo Zeng   +8 more
wiley   +1 more source

Comparison of Skin Permeation and Putative Anti-Inflammatory Activity of Commercially Available Topical Products Containing Ibuprofen and Diclofenac

Journal of Pain Research, 2020
Julie Pradal GlaxoSmithKline Consumer Healthcare S.A, Nyon 1260, SwitzerlandCorrespondence: Julie PradalGSK Consumer Healthcare S.A., Route De l’Etraz 2, Nyon 1260, SwitzerlandTel +41 22 567 26 72Email julie.x.pradal@gsk.comPurpose: The therapeutic
Pradal J
doaj  

Alkylglycerol Derivatives, a New Class of Skin Penetration Modulators

Molecules, 2017
The absorption modulating activity of two alkylglycerol derivatives (batyl and chimyl alcohol) on skin barrier properties was evaluated. Biophysical tests such as transepidermal water loss (TEWL) and attenuated total reflectance–Fourier transform ...
Sergio Alberto Bernal-Chávez, Lilia Yazmín Pérez-Carreto, María Guadalupe Nava-Arzaluz, Adriana Ganem-Rondero   +3 more
doaj   +1 more source

Skin absorption of felbinac solid nanoparticles in gel formulation containing l-menthol and carboxypolymethylene. [PDF]

J Pharm Health Care Sci, 2023
Kadowaki R, Ogata F, Fushiki A, Daimyo S, Deguchi S, Otake H, Nagata M, Sasaki H, Kawasaki N, Nagai N.   +9 more
europepmc   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source