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In vitro modelling of extracellular matrix changes during skin aging: from static 2D to 3D dynamic microphysiological systems [PDF]

open access: yesMicrosystems & Nanoengineering
Skin aging results from a combination of intrinsic factors and exogenous stimuli, leading to changes in the structure and components of the extracellular matrix (including the skin basement membrane), which directly influence the aging process.
Yu Yao   +9 more
doaj   +2 more sources

Osteolineage cells ablation promotes skin aging phenotypes via dysregulated bone marrow macrophages [PDF]

open access: yesiScience
Summary: Clinical evidence links bone loss to skin thinning during aging, yet the causal role of bone in skin regulation remains unclear. Here, we show that the partial ablation of osteolineage cells induces skin aging, manifested by dermal thinning ...
Sen-Yao Zhang   +7 more
doaj   +2 more sources

Advances in the application of multi-omics analysis in skin aging [PDF]

open access: yesFrontiers in Aging
Skin aging is a progressive decline in the structural integrity and physiological function of the skin, driven by a complex interplay of intrinsic and extrinsic factors. Consequently, skin aging is classified into intrinsic and extrinsic aging. Intrinsic
Boquan Long   +8 more
doaj   +2 more sources

Research on the mechanisms of plant bioactive metabolites in anti-skin aging and future development prospects [PDF]

open access: yesFrontiers in Pharmacology
With the accelerated pace of modern life and the influence of various environmental factors, skin aging has become a widespread health and aesthetic concern worldwide.
Haoran Wang   +3 more
doaj   +2 more sources

The Skin Epilipidome in Stress, Aging, and Inflammation

open access: yesFrontiers in Endocrinology, 2021
Lipids are highly diverse biomolecules crucial for the formation and function of cellular membranes, for metabolism, and for cellular signaling. In the mammalian skin, lipids additionally serve for the formation of the epidermal barrier and as surface ...
Florian Gruber   +10 more
doaj   +1 more source

Plant-Derived Extracts Plus Vitamin E and/or Aloe Vera Protect Against Intrinsic/Extrinsic Stressor in Human Skin: In Vitro and Clinical Evidence

open access: yesFrontiers in Bioscience-Landmark, 2023
Background: Humans are exposed to physical, biological, chemical, and psychological stressor throughout their life span. In recent years many medicinal plants have been shown to induce stress adapting and protective functions.
Ganesh Diwakar   +4 more
doaj   +1 more source

Facial Skin Aging Stages in Chinese Females

open access: yesFrontiers in Medicine, 2022
BackgroundFacial skin is exposed to the environment, which marks it with obvious signs of aging. Based on multi-dimensional non-invasive evaluation data, female facial skin can be characterized in detail.
Xiao-xiao Yang   +11 more
doaj   +1 more source

Skin-Aging Pigmentation: Who Is the Real Enemy?

open access: yesCells, 2022
Skin aging is induced and sustained by chronological aging and photoaging. Aging skin pigmentation such as mottled pigmentation (senile lentigo) and melasma are typical signs of photoaging. The skin, like other human organs, undergoes cellular senescence,
Jin Cheol Kim   +2 more
doaj   +1 more source

Skin aging risk factors: A nationwide population study in Mongolia risk factors of skin aging

open access: yesPLoS ONE, 2022
The world population is aging and no country is immune to the consequences. We are not aware of any country-specific skin aging risk factors data for the Mongolian people.
Tuya Nanzadsuren   +6 more
doaj   +2 more sources

Skin aging associated with chromium among rural housewives in northern China

open access: yesEcotoxicology and Environmental Safety, 2023
Previous studies have found associations between chromium exposure and skin damage. However, few studies have focused on both chromium and skin aging. This study aimed to assess the degree of skin aging symptoms and estimate the relationship between hair
Jigen Na   +6 more
doaj   +1 more source

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