Results 41 to 50 of about 446,329 (344)

Age and sun exposure-related widespread genomic blocks of hypomethylation in nonmalignant skin [PDF]

open access: yes, 2015
BACKGROUND: Aging and sun exposure are the leading causes of skin cancer. It has been shown that epigenetic changes, such as DNA methylation, are well established mechanisms for cancer, and also have emerging roles in aging and common disease.
Amy R Vandiver   +10 more
core   +1 more source

Aging and aerobic fitness affect the contribution of noradrenergic sympathetic nerves to the rapid cutaneous vasodilator response to local heating [PDF]

open access: yes, 2011
Sedentary aging results in a diminished rapid cutaneous vasodilator response to local heating. We investigated whether this diminished response was due to altered contributions of noradrenergic sympathetic nerves; assessing 1) the age-related decline and,
Alan D. Ruddock   +6 more
core   +1 more source

Phlorotannin Extracts from Fucales Characterized by HPLC-DAD-ESI-MSn: Approaches to Hyaluronidase Inhibitory Capacity and Antioxidant Properties [PDF]

open access: yes, 2019
Purified phlorotannin extracts from four brown seaweeds (Cystoseira nodicaulis (Withering) M. Roberts, Cystoseira tamariscifolia (Hudson) Papenfuss, Cystoseira usneoides (Linnaeus) M.
Andrade, Paula   +6 more
core   +1 more source

The skin aging exposome [PDF]

open access: yesJournal of Dermatological Science, 2017
The term "exposome" describes the totality of exposures to which an individual is subjected from conception to death. It includes both external and internal factors as well as the human body's response to these factors. Current exposome research aims to understand the effects all factors have on specific organs, yet today, the exposome of human skin ...
Krutmann, Jean   +4 more
openaire   +2 more sources

The Skin and Inflamm-Aging

open access: yesBiology, 2023
With its unique anatomical location facing both the external and internal environment, the skin has crucial functions, including shielding the body from damage caused by ultraviolet radiation and chemicals, preventing water loss, acting as a primary barrier against pathogens, participating in metabolic processes like vitamin D production and ...
Rashi Agrawal, Anne Hu, Wendy B. Bollag
openaire   +3 more sources

Prospective randomized controlled pilot study on the effects of almond consumption on skin lipids and wrinkles. [PDF]

open access: yes, 2019
ObjectiveAlmonds are a rich source of fatty acids and antioxidants, and their supplementation is known to significantly modulate serum lipids. The effects of almond on the skin's lipid barrier and the appearance of wrinkles have not yet been elucidated ...
Burney, Waqas A   +7 more
core   +1 more source

In Silico Approaches and the Role of Ontologies in Aging Research [PDF]

open access: yes, 2013
The 2013 Rostock Symposium on Systems Biology and Bioinformatics in Aging Research was again dedicated to dissecting the aging process using in silico means.
Busch, Hauke   +14 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Could Inflammaging and Its Sequelae Be Prevented or Mitigated? [PDF]

open access: yes, 2019
Aged humans display a chronic and low-grade inflammation, termed "inflammaging", which has been potentially linked to the subsequent development of some aging-associated systemic disorders, including type 2 diabetes, atherosclerotic cardiovascular ...
Elias, Peter M, Man, Mao-Qiang
core  

Klotho mice: a novel wound model of aged skin. [PDF]

open access: yes, 2014
BackgroundAs the elderly population continues to expand, it becomes increasingly important to develop treatments to improve wound healing in the elderly.
Yamashita, Ken   +3 more
core   +2 more sources

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