Results 81 to 90 of about 446,329 (344)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Skin Aging Estimation Scheme Based on Lifestyle and Dermoscopy Image Analysis

open access: yesApplied Sciences, 2019
Besides genetic characteristics, people also undergo a process of skin aging under the influence of diverse factors such as sun exposure, food intake, sleeping patterns, and drinking habits, which are closely related to their personal lifestyle.
Jehyeok Rew   +3 more
doaj   +1 more source

Photochemoprotection of Caulera Spp Active Component on Rat Model Skin [PDF]

open access: yes, 2013
Caulerpa spp. including seaweed and macro-algae can be found in a large number at Coastal Serangan, Bali-Indonesia. Caulerpa spp was historically used for food and vegetable.
Mantik-Astawa, A. N. (and)   +2 more
core  

気管支喘息患者における細胞性免疫,ガンジダ抗原に対する遅延型反応の抑制 [PDF]

open access: yes, 1992
Delayed cutaneous hypersensitivity towards Candida albicans was examined in 200 patients with bronchial asthma in relation to patient age and the level of total IgE. 1.
Harada, Hideo   +7 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Skin Changes in the Elderly People – How Strong is the Influence of the UV Radiation on Skin Aging? [PDF]

open access: yes, 2010
Just like every other part of the organism, the skin ages as a result of the passage of time. That process is called chronologic or intrinsic aging. However, skin is also exposed to external insults, such as UV radiation, which is the most influential ...
Ivan Krolo   +5 more
core   +1 more source

Fifty-kDa Hyaluronic Acid Upregulates Some Epidermal Genes without Changing TNF-α Expression in Reconstituted Epidermis [PDF]

open access: yes, 2011
Background: Due to its strong water binding potential, hyaluronic acid (HA) is a well-known active ingredient for cosmetic applications. However, based on its varying molecular size, skin penetration of HA may be limited. Recent studies have demonstrated
B. Malle   +15 more
core   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

New Insights into the Anti-Aging Mechanism of Collagen Peptides—Emphasis on Lysosomes and Mitochondria Function

open access: yesMolecules
With the intensification of social aging and the improvement of living standards, delaying aging has become a focus of common concern, especially in regard to skin aging.
Wei Huang   +3 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

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