Results 101 to 110 of about 598,588 (305)

Influence of the sebaceous gland density on the stratum corneum lipidome [PDF]

, 2018
The skin surface lipids (SSL) result from the blending of sebaceous and epidermal lipids, which derive from the sebaceous gland (SG) secretion and the permeability barrier of the stratum corneum (SC), respectively.
Camera, Emanuela, Kozul, Nina, Ludovici, Matteo, Materazzi, Stefano, Picardo, Mauro, Risoluti, Roberta   +5 more
core   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Interaction between the microbiota and the skin barrier in aging skin: a comprehensive review

Frontiers in Physiology
The interplay between the microbes and the skin barrier holds pivotal significance in skin health and aging. The skin and gut, both of which are critical immune and neuroendocrine system, harbor microbes that are kept in balance.
Yu Ri Woo, Hei Sung Kim
doaj   +1 more source

Incontinence-associated dermatitis: reducing adverse events [PDF]

, 2016
Incontinence-associated dermatitis (IAD) is a common problem in patients with faecal and/or urinary incontinence. Urine alters the normal skin flora and increases permeability of the stratum corneum and faecal enzymes on the skin contribute to skin ...
Blaak J, Chatham N, Hall KD, Heywood N, Hunter S, Jacobson TM, Kottner J, Lewis-Byers K, Newman D, Nix D, Trojahn C   +10 more
core   +1 more source

Facilitating Expedited Drug Approval– the Past, Present, and Future of Clinical Trials for Pediatric Rheumatic Disease

Arthritis Care &Research, Accepted Article.
Pamela F. Weiss, Hermine I. Brunner
wiley   +1 more source

PEDOT‐Based Eutectogel Electrode Arrays for Enhanced High‐Resolution Electrogastrography: Fabrication, Stability, and Wearable Performance

Advanced Functional Materials, EarlyView.
Here, we present a high‐density PEDOT eutectogel electrode array for enhanced body surface gastric mapping. Silver electrodes are blade‐coated onto flexible substrates, followed by electrogelation of PEDOT:PSS and the deposition of a PEDOT:LS eutectogel.
Christopher Slaughter, Luke Gatecliff, Xudong Tao, Ruben Ruiz‐Mateos Serrano, Amy T. Jin, Matias L. Picchio, Daniele Mantione, Antonio Dominguez‐Alfaro, George G. Malliaras   +8 more
wiley   +1 more source

The relationship between the skin microecology and the skin barrier

Pifu-xingbing zhenliaoxue zazhi
With the development of metagenomics sequencing and spatial transcriptomics, the door to the "microscopic world" of the skin surface has gradually been opened, and the "inhabitants" on the "habitat" of the skin have gradually become well-known.
LIN Tianyi, CHEN Jiaoquan, OU Shanshan, WU Weihong, ZOU Hui, CHEN Ziyan, PENG Liqian, CHEN Quan, LI Huaping, ZHU Huilan   +9 more
doaj   +1 more source

Particulate matter causes skin barrier dysfunction

JCI Insight, 2021
The molecular mechanisms that underlie the detrimental effects of particulate matter (PM) on skin barrier function are poorly understood. In this study, the effects of PM2.5 on filaggrin (FLG) and skin barrier function were investigated in vitro and in ...
Byung Eui Kim, Jihyun Kim, Elena Goleva, Evgeny Berdyshev, Jinyoung Lee, Kathryn A. Vang, Un Ha Lee, SongYi Han, Susan Leung, Clifton F. Hall, Na-Rae Kim, Irina Bronova, Eu Jin Lee, Hye-Ran Yang, Donald Y.M. Leung, Kangmo Ahn   +15 more
doaj   +1 more source

The attachment system and physiology in adulthood: normative processes, individual differences, and implications for health. [PDF]

, 2014
Attachment theory provides a conceptual framework for understanding intersections between personality and close relationships in adulthood. Moreover, attachment has implications for stress-related physiology and physical health.
Ainsworth, Avitsur, Baumeister, Beedie, Biomarker Definitions Working Group, Bolger, Bowlby, Bowlby, Bowlby, Brennan, Brooks, Bullmore, Carmichael, Coan, Coan, Collins, Collins, Collins, Collins, Dallman, DeVries, DeWall, Diamond, Diamond, Diamond, Diamond, Dickerson, Eisenberger, Epel, Fraley, Fraley, Gailliot, Gouin, Hagger, Hasler, Hazan, Hazan, Hicks, Hofer, Holland, Holt-Lunstad, Kane, Kidd, Kiecolt-Glaser, Kiecolt-Glaser, Kiecolt-Glaser, Kirschbaum, Kurzban, Laurenceau, Lovallo, Master, Maunder, Maunder, McClure, McEwen, McWilliams, Mikulincer, Miller, Molden, Pasch, Peters, Pietromonaco, Polan, Powers, Quirin, Ridker, Roberts, Robles, Robles, Robles, Roisman, Salvy, Sanders, Sapolsky, Sbarra, Scharfe, Souza, Stumvoll, Taylor, Troxel, Troxel, Troxel, Troxel, Uchino, Vaishnavi, Vormbrock, Vrtička, Vrtička, Walburn   +88 more
core   +1 more source

Liquid Crystalline Inverted Lipid Phases and Reverse Micelles in Drug Delivery: From Molecular Design to Therapeutic Potential

Advanced Functional Materials, EarlyView.
Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu, Mulazim Hussain Asim, Soheil Haddadzadegan, Andreas Bernkop‐Schnürch   +3 more
wiley   +1 more source