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The skin: an indispensable barrier
Experimental Dermatology, 2008Abstract: The skin forms an effective barrier between the organism and the environment preventing invasion of pathogens and fending off chemical and physical assaults, as well as the unregulated loss of water and solutes. In this review we provide an overview of several components of the physical barrier, explaining how barrier function is regulated ...
Ehrhardt Proksch +2 more
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Skin Barrier Function and the Microbiome
International Journal of Molecular Sciences, 2022 Human skin is the largest organ and serves as the first line of defense against environmental factors. The human microbiota is defined as the total microbial community that coexists in the human body, while the microbiome refers to the collective genome of these microorganisms.
Hyun Ji Lee, Miri Kim
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Cutaneous Barriers and Skin Immunity
2021The skin barrier provides us with several lines of protection from outside hazards. Its most outward layers, the stratum corneum and the epidermis seal our body with an acidic, dry, and rather cool surface, hostile to microbes. Yet, there are also fine-tuned interactions between the mostly commensal microbiota on top of the skin surface, with ...
Köberle, M. +4 more
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Matching the skin barrier to the skin type
British Journal of Nursing, 2011Peristomal skin problems are thought to be common (Herlufsson et al, 2006; Williams et al, 2010 ), and can interfere with the security of stoma products. Stoma patients are reliant on the integrity of their peristomal skin to maintain a normal lifestyle. Bekkers et al (1996) highlighted that, if the peristomal skin becomes damaged, it not only affects
Hyacinth, Thompson +3 more
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Clinics in Dermatology, 2019
The skin barrier is mainly present in the stratum corneum (SC), composed of corneocytes surrounded by intercellular lipid lamellae, and attached by corneodesmosome. The tight junction attached to the lateral walls of keratinocytes in the upper part of the stratum granulosum is also included in the skin barrier.
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The skin barrier is mainly present in the stratum corneum (SC), composed of corneocytes surrounded by intercellular lipid lamellae, and attached by corneodesmosome. The tight junction attached to the lateral walls of keratinocytes in the upper part of the stratum granulosum is also included in the skin barrier.
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Archives of Dermatology, 1961
All of us will recall the concept of the blood-brain barrier from medical school days. Since then, the selective permeability of cerebral capillaries has been adequately demonstrated. It appears that a highly fortunate filter exists, which protects the neuron from a few of the circulating poisons arising from within or without.
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All of us will recall the concept of the blood-brain barrier from medical school days. Since then, the selective permeability of cerebral capillaries has been adequately demonstrated. It appears that a highly fortunate filter exists, which protects the neuron from a few of the circulating poisons arising from within or without.
openaire +2 more sources
Skin barrier and dry skin in the mature patient
Clinics in Dermatology, 2018Dry skin is the most common clinical manifestation of dermatologic diseases, and it presents with itching, redness, and desquamation-signs and clinical manifestations that are not only physically uncomfortable but also affect patients psychologically.
Tončić, Ružica Jurakić +3 more
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Water, salts and skin barrier of normal skin
Skin Research and Technology, 2003Background: We recently reported that open application of seawater for 20 min ameliorated experimental irritant contact dermatitis induced by sodium lauryl sulphate (SLS) cumulative irritation. The efficacy was overall contributed by 500 mm of sodium chloride (NaCI) and 10 mm of potassium chloride (KCl), which are consistent with the each concentration
Yusuke, Yoshizawa +3 more
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Moisturization and skin barrier function
Dermatologic Therapy, 2004Over the past decade, great progress has been made toward elucidating the structure and function of the stratum corneum (SC), the outermost layer of the epidermis. SC cells (corneocytes) protect against desiccation and environmental challenge by regulating water flux and retention.
A V, Rawlings, C R, Harding
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Skin barrier and microbiome in acne
Archives of Dermatological Research, 2017Acne is an immune-mediated chronic inflammatory disease. Although several factors are involved in its pathophysiology, this process is not completely understood. Androgen hormone activity increases sebum production inside the pilosebaceous follicle, adjusting the environment for the development of Propionibacterium acnes which triggers inflammation ...
M A, Rocha, E, Bagatin
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