Results 1 to 10 of about 17,877 (112)

Role of Src and Cortactin in Pemphigus Skin Blistering [PDF]

Frontiers in Immunology, 2019
Autoantibodies against desmoglein (Dsg) 1 and Dsg3 primarily cause blister formation in the autoimmune disease pemphigus vulgaris (PV). Src was proposed to contribute to loss of keratinocyte cohesion.
Daniela Kugelmann, Vera Rötzer, Elias Walter, Desalegn Tadesse Egu, Michael Tobias Fuchs, Franziska Vielmuth, Hilda Vargas-Robles, Michael Schnoor, Michael Hertl, Rüdiger Eming, Klemens Rottner, Klemens Rottner, Ansgar Schmidt, Volker Spindler, Volker Spindler, Jens Waschke   +15 more
doaj   +2 more sources

Genetics and Omics Analysis of Autoimmune Skin Blistering Diseases [PDF]

Frontiers in Immunology, 2019
Autoimmune blistering diseases (AIBDs) of the skin are characterized by autoantibodies against different intra-/extracellular structures within the epidermis and at the basement membrane zone (BMZ). Binding of the antibodies to their target antigen leads
Michael Olbrich, Michael Olbrich, Axel Künstner, Axel Künstner, Mareike Witte, Hauke Busch, Hauke Busch, Anke Fähnrich, Anke Fähnrich   +8 more
doaj   +2 more sources

A rare case of skin blistering and esophageal stenosis in the course of epidermolysis bullosa - case report and literature review [PDF]

BMC Gastroenterology, 2018
Background Epidermolysis bullosa (EB) constitutes a heterogenous group of rare multisystem genetically transmitted disorders comprising several blistering muco-cutaneous diseases with a monogenic basis and either autosomal dominant or autosomal recessive
Agata Michalak, Halina Cichoż-Lach, Beata Prozorow-Król, Leszek Buk, Monika Dzida   +4 more
doaj   +2 more sources

Skin Barrier and Autoimmunity—Mechanisms and Novel Therapeutic Approaches for Autoimmune Blistering Diseases of the Skin

Frontiers in Immunology, 2019
One of the most important functions of the skin besides regulating internal body temperature includes formation of the barrier between the organism and the external environment, hence protecting against pathogen invasion, chemical and physical assaults ...
Natalie E. Stevens, Allison J. Cowin, Zlatko Kopecki   +2 more
doaj   +3 more sources

Editorial: Skin Blistering Diseases [PDF]

Frontiers in Medicine, 2019
Cristina Has, Kyle T. Amber, Dedee F. Murrell, Philippe Musette, Ralf J. Ludwig   +4 more
doaj   +2 more sources

The flavonoid luteolin inhibits Fcγ-dependent respiratory burst in granulocytes, but not skin blistering in a new model of pemphigoid in adult mice.

PLoS ONE, 2012
Bullous pemphigoid is an autoimmune blistering skin disease associated with autoantibodies against the dermal-epidermal junction. Passive transfer of antibodies against BP180/collagen (C) XVII, a major hemidesmosomal pemphigoid antigen, into neonatal ...
Eva Oswald, Alina Sesarman, Claus-Werner Franzke, Ute Wölfle, Leena Bruckner-Tuderman, Thilo Jakob, Stefan F Martin, Cassian Sitaru   +7 more
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Involvement of palms and soles in patients with autoimmune bullous diseases: a comparative analysis of a diagnostically relevant localization

Frontiers in Immunology, 2023
IntroductionThe involvement of palms and soles is variable among disease entities belonging to autoimmune bullous diseases (AIBD). We present our own clinical-laboratory experience concerning presentations of skin lesions on palms and soles in the ...
Magdalena Jałowska, Maciej Spałek, Monika Bowszyc-Dmochowska, Justyna Gornowicz- Porowska, Marian Dmochowski   +4 more
doaj   +1 more source

Characterization of the skin microbiota in bullous pemphigoid patients and controls reveals novel microbial indicators of disease

Journal of Advanced Research, 2023
Introduction: Bullous pemphigoid (BP) is the most common autoimmune blistering disease. It predominately afflicts the elderly and is significantly associated with increased mortality.
Meriem Belheouane, Britt M. Hermes, Nina Van Beek, Sandrine Benoit, Philippe Bernard, Kossara Drenovska, Sascha Gerdes, Regine Gläser, Matthias Goebeler, Claudia Günther, Anabelle von Georg, Christoph M. Hammers, Maike M. Holtsche, Bernhard Homey, Orsolya N. Horváth, Franziska Hübner, Beke Linnemann, Pascal Joly, Dalma Márton, Aikaterini Patsatsi, Claudia Pföhler, Miklós Sárdy, Laura Huilaja, Snejina Vassileva, Detlef Zillikens, Saleh Ibrahim, Christian D. Sadik, Enno Schmidt, John F. Baines   +28 more
doaj   +1 more source

Cytoskeletal Regulation of Inflammation and Its Impact on Skin Blistering Disease Epidermolysis Bullosa Acquisita [PDF]

International Journal of Molecular Sciences, 2016
Zlatko Kopecki, Ralf J Ludwig, Allison J Cowin   +2 more
exaly   +2 more sources

The relevance of complement in pemphigoid diseases: A critical appraisal

Frontiers in Immunology, 2022
Pemphigoid diseases are autoimmune chronic inflammatory skin diseases, which are characterized by blistering of the skin and/or mucous membranes, and circulating and tissue-bound autoantibodies.
Cristian Papara, Cristian Papara, Christian M. Karsten, Hideyuki Ujiie, Enno Schmidt, Enno Schmidt, Leon F. Schmidt-Jiménez, Adrian Baican, Patricia C. Freire, Kentaro Izumi, Katja Bieber, Matthias Peipp, Admar Verschoor, Admar Verschoor, Ralf J. Ludwig, Ralf J. Ludwig, Jörg Köhl, Jörg Köhl, Detlef Zillikens, Christoph M. Hammers, Christoph M. Hammers   +20 more
doaj   +1 more source