Results 231 to 240 of about 1,233,961 (300)

A novel EGFR-targeted photosensitizer for the theranostics of skin cancer. [PDF]

Int J Pharm X
Li H, Li H, Qi S, Tang X, Zhao S, Bian X, Tian B, Zhang H, Wei Y, Jia D, Han X, Fan Q.   +11 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Nasal Reconstruction After Skin Cancer Excision: Clinical and Patient-Reported Outcomes from a Retrospective Study. [PDF]

J Clin Med
Battaglia F, Colonna MR, Filistad S, Giuffrida R, Delia G.   +4 more
europepmc   +1 more source

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

Advanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia, Chenfei Kong, Xiaoming Zhao, Naixu Shi, Jinlan Jiang, Ping Li   +5 more
wiley   +1 more source

Non-invasive epidermis sampling for DNA methylation-based prediction of skin cancer phenotypes. [PDF]

NPJ Precis Oncol
Rodríguez-Paredes M, Feng Y, Gilliam O, Wegner K, Raddatz G, Grönniger E, Lyko F.   +6 more
europepmc   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

Evidence Synthesis of Artificial Intelligence Performance in Skin Cancer Diagnosis. [PDF]

Int J Dermatol
Kiss N, Boostani M.
europepmc   +1 more source

Visualization of Endosomal Escape of Intracellularly Delivered Protein With Unexpected Photochemical Internalization of Trypan Blue

Advanced Science, EarlyView.
TB, a conventional cell viability dye, acts as both a fluorescence modulator (quenching GFP fluorescence upon protein binding and recovering it upon release) and a photosensitizer that triggers endosomal escape via photochemical internalization (PCI) under 590 nm light.
Zhongqi Yao, Zhan Shi, Peng Hu, Changping Wang, Hui Wang   +4 more
wiley   +1 more source

Nanotechnology in Skin Cancer Therapy: Recent Progress in Targeted Delivery. [PDF]

Kaohsiung J Med Sci
Yu HP, Hsu CY, Fang JY, Lin ZC.
europepmc   +1 more source