Results 71 to 80 of about 6,921,908 (377)

Serological response following COVID-19 vaccines in patients living with HIV: a dose–response meta-analysis

open access: yesScientific Reports, 2023
To quantify the pooled rate and risk ratio of seroconversion following the uncomplete, complete, or booster dose of COVID-19 vaccines in patients living with HIV.
Qian Zhou   +5 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Total Body Skin Exam and Number Needed to Screen [PDF]

open access: yes, 2019
Introduction/Background: Skin cancer screening could impact mortality and morbidity in US adults; however, the effectiveness of widespread screening remains unclear.
Bui, Michael   +4 more
core   +1 more source

Cervical Cancer-Associated Human Papillomavirus 16 E7 Oncoprotein Inhibits Induction of Anti-Cancer Immunity by a CD4+ T Cell Dependent Mechanism [PDF]

open access: yes, 2009
Attempts to develop therapeutic vaccines against cervical cancer have been proven difficult. One of the major causes of the failure is due to the use of the wrong mouse models based on transplantable tumours in testing the efficacy of vaccines.
Germain J. Fernando   +3 more
core   +2 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Patient Perspectives on the Use of Artificial Intelligence for Skin Cancer Screening: A Qualitative Study.

open access: yesJAMA dermatology, 2020
Importance The use of artificial intelligence (AI) is expanding throughout the field of medicine. In dermatology, researchers are evaluating the potential for direct-to-patient and clinician decision-support AI tools to classify skin lesions. Although AI
C. Nelson   +12 more
semanticscholar   +1 more source

An RNAi Screen Reveals an Essential Role for HIPK4 in Human Skin Epithelial Differentiation from iPSCs

open access: yesStem Cell Reports, 2017
Molecular mechanisms responsible for the development of human skin epithelial cells are incompletely understood. As a consequence, the efficiency to establish a pure skin epithelial cell population from human induced pluripotent stem cells (hiPSCs ...
Lionel Larribère   +8 more
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Computer-aided diagnosis of skin cancer based on soft computing techniques

open access: yesOpen Medicine, 2020
Skin cancer is a type of disease in which malignant cells are formed in skin tissues. However, skin cancer is a dangerous disease, and an early detection of this disease helps the therapists to cure this disease.
Zhiying Xu   +3 more
semanticscholar   +1 more source

Automatic segmentation of skin cancer images using adaptive color clustering [PDF]

open access: yes, 2006
This paper presents the development of an adaptive image segmentation algorithm designed for the identification of the skin cancer and pigmented lesions in dermoscopy images. The key component of the developed algorithm is the Adaptive Spatial K-Means (A-
Ilea, Dana E., Whelan, Paul F.
core  

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