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Eosinophils in skin diseases [PDF]
Seminars in Immunopathology, 2021 AbstractEosinophil infiltration is a common finding in a broad spectrum of skin diseases, despite the fact that the skin is devoid of eosinophils under physiologic conditions. Although cutaneous eosinophilia is reactive, cytokine-mediated in most cases, diseases with an intrinsic mutation-mediated clonal expansion of eosinophils can also manifest on ...
Hans-Uwe Simon +5 more
openaire +4 more sources
Advances in the study of macrophage polarization in inflammatory immune skin diseases
Journal of Inflammation, 2023 When exposed to various microenvironmental stimuli, macrophages are highly plastic and primarily polarized into the pro-inflammatory M1-type and the anti-inflammatory M2-type, both of which perform almost entirely opposing functions.
Tingting Xia +10 more
semanticscholar +1 more source
Pharmaceutics, 2023 The topical route is the most appropriate route for the targeted delivery of drugs to skin tissues for the treatment of local skin diseases; however, the stratum corneum (SC), the foremost layer of the skin, acts as a major barrier.
E. A. Madawi +7 more
semanticscholar +1 more source
The role of short-chain fatty acids in inflammatory skin diseases
Frontiers in Microbiology, 2023 Short-chain fatty acids (SCFAs) are metabolites of gut microbes that can modulate the host inflammatory response, and contribute to health and homeostasis.
Xian-jun Xiao +13 more
semanticscholar +1 more source
Gut microbes, 2022 The human intestine hosts diverse microbial communities that play a significant role in maintaining gut-skin homeostasis. When the relationship between gut microbiome and the immune system is impaired, subsequent effects can be triggered on the skin ...
Md. Rayhan Mahmud +10 more
semanticscholar +1 more source
Nature Communications, 2021 Fibrotic skin disease represents a major global healthcare burden, characterized by fibroblast hyperproliferation and excessive accumulation of extracellular matrix.
Cheng-Cheng Deng +10 more
semanticscholar +1 more source
Prevalence of most common skin diseases in Europe: a population‐based study
Journal of the European Academy of Dermatology and Venereology, 2022 The assessment of the prevalence of diseases is of primary importance in planning health policies. No complete data on the prevalence of skin diseases across European countries are available.
M. Richard +8 more
semanticscholar +1 more source
Theranostics, 2022 Skin diseases are the fourth leading cause of nonfatal and chronic skin diseases, acting as a global burden and affecting the world economy. Skin diseases severely impact the patients' quality of life and have influenced their physical and mental state ...
Fei Qu +3 more
semanticscholar +1 more source