Results 41 to 50 of about 350,517 (216)

Pattern of skin diseases and occupational dermatoses in veterinarians and veterinary workers of Kashmir

Indian Dermatology Online Journal, 2017
Background: Across the globe, skin disorders represent a frequent occupational concern for many health professionals including veterinarians and there is a serious impact of skin diseases on their lives and careers.
Sumaya Zeerak, Iffat Hassan, Farhan Rasool, Yasmeen J Bhat, Safia Bashir   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Clinicopathological Study of Non-Infectious Erythaematous Papulosquamous Skin Diseases [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Papulosquamous diseases are characterized by scaly papules and plaques with similar clinical picture which amounts to confusion and hence, a definitive histopathological diagnosis goes a long way in treatment of such diseases.
Sushma Hosamane, Muktha Pai, Thoppil Reba Philipose, Umaru Nayarmoole   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Risk of Superficial Fungal Infections in WHIM Syndrome

Dermatology and Therapy
Introduction WHIM syndrome is a rare autosomal dominant inborn error of immunity caused by gain-of-function mutations in the chemokine receptor CXCR4. Patients with WHIM syndrome frequently suffer from an increased risk for bacterial and viral infections,
Jennifer Strong, Rutha Adhanom, Caleb S. Kim, Yoshine Saito, Jasmine C. Meltzer, Patrick Hallaert, Sophia Martinez, Abigail Salancy, Heidi H. Kong, Edward W. Cowen, Leslie Castelo-Soccio, Philip M. Murphy, David H. McDermott, Isaac Brownell   +13 more
doaj   +1 more source

Impaired NLRP3 inflammasome activation by chitin underlies refractory chromoblastomycosis caused by Fonsecaea pedrosoi muriform cells

Frontiers in Immunology
IntroductionMacrophage NLRP3 activation is crucial for antifungal immunity, yet its role in chromoblastomycosis—a chronic subcutaneous mycosis typically caused by Fonsecaea pedrosoi—remains unclear.
Yao Chen, Yao Chen, Zilu Qu, Zilu Qu, Zhaolan Xie, Xiaowen Wang, Zhongsheng Tong, Zhongsheng Tong, Luoyao Yang, Luoyao Yang, Xu Zhang, Xu Zhang, Liuqing Chen, Liuqing Chen, Bilin Dong, Bilin Dong   +15 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Histopathological spectrum of skin diseases in a tertiary skin health and referral centre

Journal of Pathology of Nepal, 2019
Background: Skin diseases are very much prevalent in the developing countries. The pattern of skin diseases varies from country to country and even region to region within a country.
Ram Chandra Adhikari, Mahesh Shah, Anjani Kumar Jha   +2 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Morphological characteristics of involutive changes of epidermis in patients with malasseziasis of facial skin

Patologìâ, 2015
Many questions about the dependence of age-appropriate pathological changes of the skin on background malassezia destruction require clarification and further advance. Aim.
A. O. Makarchuk
doaj   +1 more source